Results 171 to 180 of about 19,728,514 (315)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

ACTH-Modulated Membrane Guanylate Cyclase Signaling System: Origin and Creation. [PDF]

Front Mol Neurosci, 2022
Sharma RK.
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Characterization of an Aplysia vasotocin signaling system and actions of posttranslational modifications and individual residues of the ligand on receptor activity. [PDF]

Front Pharmacol, 2023
Xu JP, Ding XY, Guo SQ, Wang HY, Liu WJ, Jiang HM, Li YD, Fu P, Chen P, Mei YS, Zhang G, Zhou HB, Jing J.   +12 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Distribution of lactone-signaling system for expression of secondary metabolite biosynthetic gene clusters in Streptomyces species. [PDF]

Essays Biochem
Teshima A, Inada K, Arakawa K.
europepmc   +1 more source

Downregulation of the Protein C Signaling System Is Associated with COVID-19 Hypercoagulability-A Single-Cell Transcriptomics Analysis. [PDF]

Viruses, 2022
Silva BRS, Jara CP, Sidarta-Oliveira D, Velloso LA, Velander WH, Araújo EP.   +5 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Influence of the neurotensin signaling system on feeding and satiety. [PDF]

Neuropharmacology
Thompson KD, Leinninger GM.
europepmc   +1 more source

Identification of an allatostatin C signaling system in mollusc Aplysia. [PDF]

Sci Rep, 2022
Jiang HM, Yang Z, Xue YY, Wang HY, Guo SQ, Xu JP, Li YD, Fu P, Ding XY, Yu K, Liu WJ, Zhang G, Wang J, Zhou HB, Susswein AJ, Jing J.   +15 more
europepmc   +1 more source