Results 131 to 140 of about 179,602 (215)

Different Paths, Similar Pressures: Divergent Drivers of Genetic Diversity Despite Convergent Genomic Signatures of Selection in Response to Urban Intensity in Two Oligolectic Bee Species. [PDF]

Mol Ecol
Baltz LM, Gardein H, Greil H, Paxton RJ, Theodorou P.   +4 more
europepmc   +1 more source

Whole-genome resequencing reveals the genomic diversity and signatures of selection in Romanov sheep. [PDF]

J Anim Sci, 2023
Cao C, Kang Y, Zhou Q, Nanaei HA, Bo D, Liu P, Bai Y, Li R, Jiang Y, Lan X, Pan C.   +10 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

HLA diversity and signatures of selection in the Maniq, a nomadic hunter-gatherer population in Southern Thailand. [PDF]

Immunogenetics
Schaschl H, Herzog T, Oberreiter V, Kutanan W, Jakobsson M, Larena M.   +5 more
europepmc   +1 more source

Signatures of selection in recently domesticated macadamia. [PDF]

Nat Commun, 2022
Lin J, Zhang W, Zhang X, Ma X, Zhang S, Chen S, Wang Y, Jia H, Liao Z, Lin J, Zhu M, Xu X, Cai M, Zeng H, Wan J, Yang W, Matsumoto T, Hardner C, Nock CJ, Ming R.   +19 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A comprehensive genome-wide analysis for signatures of selection in goat (genus Capra) revealed new candidate genes for environmental adaptation and productive traits. [PDF]

BMC Genomics
Pallotti S, Garcia AFR, Deiana G, Antonini M, Zhou J, Sun H, Renieri C, Napolioni V.   +7 more
europepmc   +1 more source

Assessing Genomic Diversity and Signatures of Selection in Chinese Red Steppe Cattle Using High-Density SNP Array. [PDF]

Animals (Basel), 2023
Hu M, Jiang H, Lai W, Shi L, Yi W, Sun H, Chen C, Yuan B, Yan S, Zhang J.   +9 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Genome-wide scan for signatures of selection in Hanwoo and Angus cattle using whole-genome sequence data. [PDF]

PLoS One
Ju Kim H, Moghaddar N, Clark S, van der Werf JHJ, de Las Heras-Saldana S.   +4 more
europepmc   +1 more source