Results 211 to 220 of about 546,808 (280)

Signatures of selection underpinning rapid coral adaptation to the world's warmest reefs. [PDF]

Sci Adv, 2022
Smith EG, Hazzouri KM, Choi JY, Delaney P, Al-Kharafi M, Howells EJ, Aranda M, Burt JA.   +7 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Signatures of selection detected from whole-genome sequencing indicate that the small body size in dwarf rabbit breeds is caused by polygenic effects with a few major loci. [PDF]

Anim Genet
Bovo S, Carneiro M, Ribani A, Bolner M, Taurisano V, Schiavo G, Schiavitto M, Bertolini F, Fontanesi L.   +8 more
europepmc   +1 more source

Genome-wide mapping of signatures of selection using a high-density array identified candidate genes for growth traits and local adaptation in chickens. [PDF]

Genet Sel Evol, 2023
Mastrangelo S, Ben-Jemaa S, Perini F, Cendron F, Biscarini F, Lasagna E, Penasa M, Cassandro M.   +7 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Identifying Signatures of Selection in Genetic Time Series [PDF]

Genetics, 2018
openaire   +2 more sources

Identification of Candidate Genes for Twinning Births in Dezhou Donkeys by Detecting Signatures of Selection in Genomic Data. [PDF]

Genes (Basel), 2022
Xie T, Zhang S, Shen W, Zhang G, Guo R, Zhang W, Cao Y, Pan Q, Liu F, Sun Y, Liu S.   +10 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Multiomics analysis reveals signatures of selection and loci associated with complex traits in pigs. [PDF]

Imeta
Liu L, Yi G, Yao Y, Liu Y, Li J, Yang Y, Liu M, Fang L, Mo D, Zhang L, Liu Y, Niu Y, Wang L, Qu X, Pan Z, Wang L, Chen M, Fan X, Chen Y, Zhang Y, Li X, Wang Z, Tang Y, Huang H, Yuan P, Liao Y, Li X, Yin Z, Liu D, Zhang D, Zhou Q, Wu W, Jiang J, Gao Y, Liu GE, Wang L, Chen Y, Li K, Groenen MAM, Tang Z.   +39 more
europepmc   +1 more source

Disentangling Signatures of Selection Before and After European Colonization in Latin Americans. [PDF]

Mol Biol Evol, 2022
Mendoza-Revilla J, Chacón-Duque JC, Fuentes-Guajardo M, Ormond L, Wang K, Hurtado M, Villegas V, Granja V, Acuña-Alonzo V, Jaramillo C, Arias W, Barquera R, Gómez-Valdés J, Villamil-Ramírez H, Silva de Cerqueira CC, Badillo Rivera KM, Nieves-Colón MA, Gignoux CR, Wojcik GL, Moreno-Estrada A, Hünemeier T, Ramallo V, Schuler-Faccini L, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Balding D, Fumagalli M, Adhikari K, Ruiz-Linares A, Hellenthal G.   +34 more
europepmc   +1 more source