Results 111 to 120 of about 5,524,481 (291)
The significance of significant figures
Clinical Chemistry, 1990 R C, Hawkins, R N, Johnson
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Interview-The-Impact-of-Reuse-on-Cultural-Significance-of-Heritage-Buildings-in-Khartoum.pdf
, 2019 This interview aims to get the general idea about interviewee's opinions on the impact of reuse on the cultural heritage significance of five selected heritage buildings in Khartoum.
Dalia Attia (6420086)
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The significance of microprogramming
ACM SIGMICRO Newsletter, 1973 Interest in the topic of microprogramming appears to have had a great growth in the middle and late 1960's, but since that time it has leveled off or declined somewhat. This paper examines the reasons behind this development and then offers a reconsideration of and a new proposal for the definition of microprogramming.This result is supported by the ...
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Identity and Significance in the Design Team
, 2006 The paper examines the nature of personal identity individuals in the design team are perceived to have, derived from behavioural evidence provided by other members of the team.
Smyth, H
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