Results 101 to 110 of about 5,524,481 (291)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Declining Significance of Gender?
Intro -- Contents -- Contributors -- Preface and Acknowledgments -- Part I. Introduction -- Chapter 1. The Declining Significance of Gender? / Francine D. Blau, Mary C. Brinton, and David B. Grusky -- Part II.
Grusky, David B. +2 more
core
New tables of Behrens' test of significance
, 1956 The Tables for using Behren's test of significance of the difference between the means of two Normal samples are already available to reasonable accuracy for all cases save those involving very small samples (Statistical Tables, Tables VI, V2).
Healy, M. J. R. +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2019 This structured interview aims to get the general idea about interviewee's opinions on the impact of reuse alterations on the cultural heritage significance of three selected heritage buildings in Khartoum.
Dalia Attia (6420086)
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Internet ArchaeologyThe assessment of significance lies at the heart of the definition and management of archaeological monuments, especially in built-up urban and suburban areas.
Andreas Picker
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
مجلة كلية الطب, 2008 Background: The asialoglycoprotein receptor (ASGP-R)
Eman Sh. AL-Obeidy +2 more
doaj