Results 61 to 70 of about 1,310,125 (265)

Promoting Significant Learning: A Case Study in Computational Chemistry

Journal of Effective Teaching in Higher Education, 2019
This paper describes various pedagogical efforts implemented to promote significant learning in a computational chemistry course. The taxonomy of significant learning advanced by Fink (2003) is used as a framework to discuss the results. In this taxonomy,
Ruben Dario Parra
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

The Significance of Blended Learning in Training

, 2023
Abstract: In blended learning, educators combine the conventional learning process with online learning to improve the learning process for learners. The concept was integrated into the traditional learning process after it became apparent that technological advancement is essential. The bottom line is that blended learning integrates face-to-face with
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Ejercicio práctico: "Estaciones para el estudio de la materia"

Investigación y Postgrado, 2004
Con el propósito de lograr una mayor comprensión de toda la dinámica de cambios que ocurren en la naturaleza, se ha implementado el ejercicio práctico "Estaciones para el Estudio de la Materia". Esta estrategia didáctica fue aplicada a una muestra de 152
Alina Isabel María De Jesús Vieira, Rosa Elena Camero   +1 more
doaj  

HUMANESCENT EXPERIENTIAL PEDAGOGY AND THE THEORY OF SIGNIFICANT LEARNING

Cogitare Enfermagem, 2015
The study aims to understand humanescent experiential pedagogy as a technology for teaching, according to the theory of significant learning.
Kisna Yasmin Andrade Alves, Viviane Euzébia Pereira Santos, Marta Silvânere Pereira Dantas, Cláudia Cristiane Filgueira Martins, Pétala Tuani Candido de Oliveira Salvador, Yole Matias Silveira de Assis   +5 more
doaj   +1 more source

Safety Profile of Ambulatory Prostatic Artery Embolization after a Significant Learning Curve: Update on Adverse Events. [PDF]

J Pers Med, 2022
Amouyal G, Tournier L, De Margerie-Mellon C, Pachev A, Assouline J, Bouda D, De Bazelaire C, Marques F, Le Strat S, Desgrandchamps F, De Kerviler E.   +10 more
europepmc   +1 more source

Significance of E-Learning as a Tool in Teaching and Learning

International Journal of Innovative Technology and Exploring Engineering, 2019
The time and age we are living now is much more different than it was few decades ago. The world is changing with great pace so are the teachings and learning methodologies. Before teaching and learning methods mainly focused within classroom confines and do not include all the factors that could impact teaching and learning outcomes. But now the world
openaire   +1 more source