Results 101 to 110 of about 42,464 (273)

Development of enzyme-linked immunosorbent assay for rapid determination of sildenafil in adulterated functional foods [PDF]

, 2011
Yang Song, Yanfei Wang, Yuanming Zhang, S. Wang   +3 more
openalex   +1 more source

AIE‐Mediated In Situ Monitoring of Protein Aggregates During Coagulation and Screening of Anticoagulant Agents

Aggregate, Volume 7, Issue 1, January 2026.
The process of screening active monomers via BioSTAS technology. (A) Analyzing the properties and luminescence mechanism of an AIE molecule through density functional theory and MD simulation. (B) The establishment of a screening model, including biosensing and affinity chromatography. (C) Screening and identification of active substances.
Shuxian Zhang, Hui Yuan, Lingling Yang, Xiaoxuan Fan, Keshuai Liu, Rui Mai, Wangyan Zhao, Cheng Liu, Qiang Han, Yongjian Ai, Qionglin Liang, Xueqin Ma, Guoning Chen   +12 more
wiley   +1 more source

Evaluation of Sildenafil and Tadalafil for Reversing Constriction of Fetal Arteries in a Human Placenta Perfusion Model

HYPERTENSION, 2018
Fetal growth restriction resulting from reduced placental blood perfusion is a major cause of neonatal morbidity and mortality. Aside from intense surveillance and early delivery, there is no treatment for fetal growth restriction.
R. Walton, L. Reed, S. Estrada, Stacey S Schmiedecke, Diana L. Villazana-Kretzer, P. Napolitano, N. Ieronimakis   +6 more
semanticscholar   +1 more source

Evaluation of the Tolerability of Intermittent Intravenous Sildenafil in Pediatric Patients With Pulmonary Hypertension [PDF]

, 2016
Robyn A. Fender, Ty Hasselman, Yanzhi Wang, Aaron A. Harthan   +3 more
openalex   +1 more source

No QTcF Prolongation with Sepiapterin: Results From a Thorough QT Study in Healthy Subjects at Therapeutic and Supratherapeutic Doses

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Sepiapterin and its major metabolite 6R‐L‐erythro‐5,6,7,8‐tetrahydrobiopterin (BH4) bind to distinct variants of phenylalanine hydroxylase (PAH), which converts excess phenylalanine to tyrosine, thereby stabilizing, enhancing, and prolonging PAH activity.
Lan Gao, Hongqi Xue, Borje Darpo, Kimberly Ingalls, Diksha Kaushik, Neil Smith, Ronald Kong, Lee Golden   +7 more
wiley   +1 more source

Sexual Dysfunction and Its Relationship With Hypogonadism and Myelopathy in Male Patients With X‐Linked Adrenoleukodystrophy

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT X‐linked adrenoleukodystrophy (ALD) is a genetic disorder with neurological and endocrine manifestations, including myelopathy and hypergonadotropic hypogonadism. Many patients experience sexual dysfunction but the underlying cause has not been clarified.
Stephanie I. W. van de Stadt, Aimy M. A. Wessel, Mirjam Langeveld, Marc Engelen, Barbara Sjouke   +4 more
wiley   +1 more source

Efficacy and safety of oral sildenafil in children with Down syndrome and pulmonary hypertension

BMC Cardiovascular Disorders, 2017
BackgroundDespite the increased risk for pulmonary hypertension in children with Down syndrome, the response to treatment with targeted therapies for pulmonary hypertension in these patients is not well characterized.
M. Beghetti, A. Rudziński, Min Zhang
semanticscholar   +1 more source

Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men [PDF]

, 2023
Ahmed Abdel Fattah, Basheer N. Elmohamady, Salah A. El Hamshary, Hosam Abu El-Nasr   +3 more
openalex   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source