Results 61 to 70 of about 453,809 (210)

Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data

BMC Genomics, 2018
Background Mixed, polyclonal Mycobacterium tuberculosis infection occurs in natural populations. Developing an effective method for detecting such cases is important in measuring the success of treatment and reconstruction of transmission between ...
Benjamin Sobkowiak, Judith R. Glynn, Rein M. G. J. Houben, Kim Mallard, Jody E. Phelan, José Afonso Guerra-Assunção, Louis Banda, Themba Mzembe, Miguel Viveiros, Ruth McNerney, Julian Parkhill, Amelia C. Crampin, Taane G. Clark   +12 more
doaj   +1 more source

Capacity building in medicines development and regulation in Africa—Overview on recent progress

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3759-3769, November 2026.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke, Emile Malan, Michael Reid, Patrick Bouic, Haylene Nell, Goonaseelan Pillai, Catriona Waitt, Bernd Rosenkranz   +7 more
wiley   +1 more source

Novel Carbazole–Acylthiourea Derivatives: Synthesis, Antimicrobial, Antioxidant, Hemocompatibility, Cytotoxicity, and ADME‐Tox Profiling

ChemistryOpen, Volume 15, Issue 11, November 2026.
We synthesized four novel carprofen‐derived carbazole–acylthiourea propanamides with selective antimicrobial activity against Staphylococcus aureus, Enterococcus faecalis, and Candida albicans. Compound 1a provides combined antioxidant and antihemolytic protection.
Carmen Limban, Ioana Cristina Marinaş, Mariana Carmen Chifiriuc, Miron Teodor Căproiu, Florea Dumitraşcu, Erzsébet‐Eleonóra Kapronczai, Irina Zarafu, Diana Camelia Nuţă, Petre Ioniţă, Speranţa Avram, Cătălina Mareş, Andra Maria Păun, Bogdan Mihai Cristea, Carmellina Daniela Bădiceanu, Ilinca Margareta Vlad, Maria Coandă, Delia Laura Popescu, Coralia Bleotu   +17 more
wiley   +1 more source

Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo. [PDF]

, 2011
Mycobacterium tuberculosis dosRS two-component regulatory system controls transcription of approximately 50 genes including hspX, acg and Rv2030c, in response to hypoxia and nitric oxide conditions and within macrophages and mice.
Hu, Y, Yanmin Hu, Hu Yanmin, Anthony R M Coates, Anthony R. M. Coates, Coates, AR, Coates Anthony R. M.   +6 more
core   +2 more sources

Self-study modules on tuberculosis 1-5 : Introduction [PDF]

Course #WB2556The Self-Study Modules on Tuberculosis is a series of educational modules designed to provide information about tuberculosis (TB) in a self-study format. The series consists of nine modules that are separated into two parts. The first part,

core   +1 more source

Hepatic B‐cell lymphoma in a wild European badger (Meles meles) in the UK

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Neoplastic diseases are considered rare in wild European badgers (Meles meles) with a single pelioid hepatocellular carcinoma, and four lymphoma cases (two T‐cell, two unclassified) in the literature. A found‐dead, elderly, male wild badger underwent postmortem examination for Mycobacterium bovis surveillance.
Shauna Anne Hilton, Malcolm Bennett, Ana Liza Ortiz, Carlo Bianco   +3 more
wiley   +1 more source

In silico structure-based drug screening of novel antimycobacterial pharmacophores by DOCK-GOLD tandem screening

International Journal of Mycobacteriology, 2017
Background: Enzymes responsible for cell wall development in Mycobacterium tuberculosis are considered as potential targets of anti-tuberculosis (TB) agents.
Junichi Taira, Takashi Ito, Hitomi Nakatani, Tomohiro Umei, Hiroki Baba, Shotaro Kawashima, Taira Maruoka, Hideyuki Komatsu, Hiroshi Sakamoto, Shunsuke Aoki   +9 more
doaj   +1 more source

Environmental Drivers of Nontuberculous Mycobacteria in Tropical Freshwater Systems

Environmental Microbiology, Volume 28, Issue 11, November 2026.
In tropical freshwater ecosystems, nontuberculous mycobacterial diversity and distribution is mainly driven by habitat and sample type, and local environmental factors such as sediment texture and depth. These findings highlight the importance of microhabitat conditions over broad biogeographic patterns in shaping mycobacterial communities.
Marine Combe, Amar Bouam, Sylvestre Dizoe, Bernard Davoust, Emilien Drancourt, Dylan Messeca, Alice Valentini, Romain Blaizot, Rodolphe Elie Gozlan   +8 more
wiley   +1 more source

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, Volume 104, Issue 10, Page 964-974, November‐December 2026.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

Multidrug-resistant tuberculosis. [PDF]

, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
Zager, Ellen M, McNerney, Ruth, McNerney Ruth, Zager Ellen M   +3 more
core   +1 more source