Results 181 to 190 of about 5,855 (222)

ChemInform Abstract: Glycosylation of Silybin.

ChemInform, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
V. KREN, J. KUBISCH, P. SEDMERA, P. HALADA, V. PRIKRYLOVA, A. JEGOROV, L. CVAK, R. GEBHARDT, J. ULRICHOVA, V. SIMANEK   +9 more
openaire   +1 more source

ChemInform Abstract: Chemistry of Silybin

ChemInform, 2015
AbstractReview: data form 1959 to 2013; 94 refs.
D. Biedermann, E. Vavrikova, L. Cvak, V. Kren   +3 more
openaire   +1 more source

UVA-photoprotective potential of silymarin and silybin

Archives of Dermatological Research, 2018
Exposure to solar radiation is a major cause of environmental human skin damage. The main constituent of solar UV light is UVA radiation (320-400 nm); however, the need for protection against UVA has been marginalized for a long time. As a result, there is still a lack of useful agents for UVA protection. In this study, the effect of silymarin (SM) and
Alena, Rajnochová Svobodová, Eva, Gabrielová, Loizos, Michaelides, Pavel, Kosina, Alena, Ryšavá, Jitka, Ulrichová, Bohumil, Zálešák, Jitka, Vostálová   +7 more
openaire   +2 more sources

Microbial transformation of silybin by Trichoderma koningii

Bioorganic & Medicinal Chemistry Letters, 2006
Microbial transformation of silybin A (1) and silybin B (2), the major hepatoprotective flavonolignan diastereomers from the fruits of Silybum marianum, with the culture broth of Trichoderma koningii gave two pairs of glucosylated derivatives.
Hyun Jung, Kim, Hae-Suk, Park, Ik-Soo, Lee   +2 more
openaire   +2 more sources

Structure of silybin: synthetic studies

J. Chem. Soc., Chem. Commun., 1972
The structure of silybin (E6) has been resolved by the synthesis of the tetra- and penta-methyl ethers of the two possible derived flavanols.
R. Hänsel, J. Schulz, A. Pelter
openaire   +1 more source

Prevention of praseodymium-induced hepatotoxicity by silybin

Toxicology and Applied Pharmacology, 1976
Abstract In rats, the hepatotoxicity of praseodymium nitrate was prevented by treatment with silybin, the main component of silymarin, a compound isolated from Silybum marianum (L.) Gaertn. A single dose (100 mg/kg) of silybin, given 1 hr before or up to 8 hr after praseodymium, almost normalized the serum activities of glutamic pyruvic and ...
B, Tuchweber, W, Trost, M, Salas, R, Sieck   +3 more
openaire   +2 more sources

Bioavailability of a silybin–phosphatidylcholine complex in dogs

Journal of Veterinary Pharmacology and Therapeutics, 2007
Liver dysfunction often is associated with an imbalance in the production and removal of free radicals derived from oxygen and nitrogen and has been managed clinically with antioxidant supplements, including silymarin extract derived from milk thistle. The potential for enhanced bioavailability of a phytosome complex containing phosphatidylcholine and ...
C R, Filburn, R, Kettenacker, D W, Griffin   +2 more
openaire   +2 more sources

Prevention by silybin of phalloidin-induced acute hepatoxicity

Toxicology and Applied Pharmacology, 1979
Abstract In mice, the acute hermorrhagic necrosis of the liver induced by phalloidin was prevented by treatment with silybin, a plant compound isolated from Silybum marianum L. Gaertn. By electron microscopy, the first changes induced by the toxin were detected at the level of the hepatocytic plasmalemma and were followed by the development of ...
B, Tuchweber, R, Sieck, W, Trost
openaire   +2 more sources

Anti-phalloidine and anti-α-amanitine action of silybin in comparison with compounds similar to structural parts of silybin

Experientia, 1978
Silybin significantly antagonises the lethal poisoning of mice with alpha-amanitine or phalloidine. In the same test, taxifolin, coniferyl alcohol, fisetin and (+)-catechin were not effective.
W, Trost, G, Halbach
openaire   +2 more sources

Effect of silybin on biliary lipid composition in rats

Pharmacological Research Communications, 1983
The authors studied the influence of Silybin in rats, administered i.p. for 7 days (daily dose of 100 mg/kg/b.w.) on the biliary lipid composition and on the maximal excretory rate of bile salts. Following this treatment, biliary cholesterol excretion was reduced, while the other lipids and bile flow were not significantly modified.
Nassuato, G, Iemmolo, RM, Lirussi, F, Orlando, R, Giacon, L, Venuti, M, Strazzabosco, M, Csomos, G, Okolicsanyi, L.   +8 more
openaire   +3 more sources