Results 51 to 60 of about 3,031 (144)

Hepatitis C Drugs: The End of the Pegylated Interferon Era and the Emergence of All-Oral, Interferon-Free Antiviral Regimens: A Concise Review

Canadian Journal of Gastroenterology and Hepatology, 2014
Between 2001 and 2011, the standard of care for chronic hepatitis C virus (HCV) infection was a combination of pegylated interferon (PEGIFN) and ribavirin (RBV).
Alan Hoi Lun Yau, Eric M Yoshida
doaj   +1 more source

Effectiveness and tolerability of direct-acting antivirals for chronic hepatitis C patients in a Southern state of Brazil

Brazilian Journal of Infectious Diseases
Background This study aimed to evaluate the clinical effectiveness in terms of sustained virological response and tolerability of available second generation direct-acting antivirals in Brazilian patients.
Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Maria Lucia Alves Pedroso, Vanessa Ferreira de Camargo Radunz, Cláudia Alexandra Pontes Ivantes, Aline Satie Oba Kuniyoshi, Roberto Pontarolo   +7 more
doaj   +1 more source

A simeprevir-inducible molecular switch for the control of cell and gene therapies. [PDF]

Nat Commun, 2023
Chin SE, Schindler C, Vinall L, Dodd RB, Bamber L, Legg S, Sigurdardottir A, Rees DG, Malcolm TIM, Spratley SJ, Granéli C, Sumner J, Tigue NJ.   +12 more
europepmc   +1 more source

Simeprevir [PDF]

, 2020
openaire   +1 more source

MicroED as a Powerful Tool for Structure Determination of Macrocyclic Drug Compounds Directly from Their Powder Formulations. [PDF]

ACS Chem Biol, 2023
Danelius E, Bu G, Wieske LHE, Gonen T.
europepmc   +1 more source

Short-Term Clinical and Immunologic Outcomes Conditional on SVR12 in Hepatitis C Virus-Associated Cryoglobulinemic Vasculitis Treated With Direct-Acting Antivirals: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Boonpheng B, Ungprasert P.
europepmc   +1 more source

Machine Learning and Molecular Modeling for Drug Repurposing Targeting Potential PI3Kα Inhibitors in Post-CoViD-19 Pulmonary Fibrosis. [PDF]

ACS Omega
Dos Santos CR, Camargo PG, Rodrigues CR, Lima CHDS, Albuquerque MG.   +4 more
europepmc   +1 more source

An Evaluation of Foreign Clinical Data in the Approval Reviews of Antimicrobial Medicines in Japan: Considering Ethnic and Regional Differences in Data Extrapolations in Accordance With Regulatory Circumstances. [PDF]

Pharmacol Res Perspect
Shimazawa R, Ikeda M.
europepmc   +1 more source

Loss of KLF15 expression characterizes proximal tubule injury in cisplatin-induced acute kidney injury: A multi-omics study. [PDF]

Curr Res Toxicol
Chen L, Xie S, Yang H, Liu X, Yang S, Wang D.   +5 more
europepmc   +1 more source

Molecular chameleons adaptability in target binding. [PDF]

Struct Dyn
Bu G, Eriksson M, Rova Danelius E.
europepmc   +1 more source