Results 41 to 50 of about 14,059 (132)

Tissue Engineering and Regenerative Medicine: Perspectives and Challenges

MedComm, Volume 6, Issue 5, May 2025.
Tissue engineering and regenerative medicine. This review presents cell therapy, extracellular vesicle therapy, and tissue engineering in regenerative medicine, highlighting their key historical milestones, clinical applications, and current challenges.
Van T. Hoang, Quyen Thi Nguyen, Trang Thi Kieu Phan, Trang H. Pham, Nhung Thi Hong Dinh, Le Phuong Hoang Anh, Lan Thi Mai Dao, Van Dat Bui, Hong‐Nhung Dao, Duc Son Le, Anh Thi Lan Ngo, Quang‐Duong Le, Liem Nguyen Thanh   +12 more
wiley   +1 more source

Targeting of phosphorylated tau at threonine 181 by a Qβ virus‐like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques

Alzheimer's &Dementia, Volume 21, Issue 3, March 2025.
Abstract INTRODUCTION Pathological accumulation of tau (pTau) contributes to various tauopathies, including Alzheimer's disease (AD), and correlates with cognitive decline. A rapid surge in tau‐targeted approaches via anti‐sense oligonucleotides, active/passive immunotherapies suggests that targeting p‐Tau is a viable strategy against tauopathies ...
Nicole M. Maphis, Jonathan Hulse, Julianne Peabody, Somayeh Dadras, Madelin J Whelpley, Manas Kandath, Colin Wilson, Sasha Hobson, Jeff Thompson, Suttinee Poolsup, Danielle Beckman, Sean P Ott, Jennifer W. Watanabe, Jodie L. Usachenko, Koen K Van Rompay, John Morrison, Reed Selwyn, Gary Rosenberg, Janice Knoefel, Bryce Chackerian, Kiran Bhaskar   +20 more
wiley   +1 more source

Dendritic Cell Vaccine Harboring Inactivated Mycobacteria Induces Immune Protection Against Tuberculosis in Murine Models and is Well Tolerated in Humans

Small Science, Volume 5, Issue 2, February 2025.
A dendritic cell vaccine harboring cell debris of Bacille Calmette‐Guérin‐infected macrophages induces T‐cell immunity and immune protection against Mycobacterium tuberculosis infection in murine models; similarly, a dendritic cell vaccine harboring Mycobacterium vaccae is well tolerated and expands T‐cell immune responses in active tuberculosis ...
Zhidong Hu, Xuhui Liu, Jing Wang, Ling Gu, Zhenyan Chen, Lu Xia, Heng Yang, Jinchuan Xu, Xuejiao Huang, Huiling Wang, Shuihua Lu, Xiao‐Yong Fan   +11 more
wiley   +1 more source

Synergy between pluripotent stem cell‐derived macrophages and self‐renewing macrophages: Envisioning a promising avenue for the modelling and cell therapy of infectious diseases

Cell Proliferation, Volume 58, Issue 2, February 2025.
This review highlights the use of pluripotent stem cell‐derived macrophages (PSCdMϕs) in modelling and treating infectious diseases and explores methods to create self‐renewing macrophages (SRMϕs). We further propose that pluripotent stem cells can be utilized as a gene editing platform to develop self‐renewing macrophages (PSRMϕs). Abstract As crucial
Dingkun Peng, Meilin Li, Zhuoran Yu, Tingsheng Yan, Meng Yao, Su Li, Zhonghua Liu, Lian‐Feng Li, Hua‐Ji Qiu   +8 more
wiley   +1 more source

Viral Live‐Attenuated Vaccines (LAVs): Past and Future Directions

Advanced Science, Volume 12, Issue 3, January 20, 2025.
Live attenuated vaccines represent a delicate equilibrium between virulence and immunogenicity during adaptation. The process of animal adaptation involves artificial selection; therefore, adapted viruses exhibit decreased pathogenicity to their original hosts and increased pathogenicity to their adapted hosts.
Yan‐Dong Tang, Yuming Li, Xue‐Hui Cai, Xin Yin   +3 more
wiley   +1 more source

Abstract Supplement Abstracts from IAS 2025, the 13th IAS Conference on HIV Science, 13 – 17 July, Kigali, Rwanda & Virtual

Journal of the International AIDS Society, Volume 28, Issue S4, July 2025.
wiley   +1 more source

Altered distribution of tissue galectins correlates with mucosal dysregulation in SIV infection. [PDF]

J Immunol
Premeaux TA, Yeung ST, Johnson SD, Moar P, Byrareddy SN, Ndhlovu LC.   +5 more
europepmc   +1 more source

Modulation of transferrin receptor by HIV-2. [PDF]

Virol J
Al-Muffti AS, Kiarie IW, Tőzsér J, Mahdi M.   +3 more
europepmc   +1 more source

2024 taxonomy update for the family Retroviridae. [PDF]

Arch Virol
Mayer J, Blanco-Melo D, Coffin JM, Gifford RJ, Johnson WE, Lindemann D, Peeters M, Sato K, Stoye J, Tachedjian G, Hatziioannou T.   +10 more
europepmc   +1 more source

Application of a novel branched-DNA assay to quantify killer immunoglobulin-like receptor (KIR) mRNA expression identifies tissue compartmentalization in naïve and SIV-infected rhesus macaques. [PDF]

J Immunol Methods
Terry K, Kroll KW, Jones RA, Reeves RK.
europepmc   +1 more source