Results 1 to 10 of about 218,831 (262)

Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity. [PDF]

, 2007
BACKGROUND: Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome.
Andrew ML Lever (60785), Anne L'Hernault (60782), Jane S Greatorex (60783), R Anthony Crowther (60784)   +3 more
core   +3 more sources

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques

Journal of Experimental Medicine, 1996
We used the simian immunodeficiency virus (SIV)/rhesus macaque model to study events that underlie sexual transmission of human immunodeficiency virus type 1 (HIV-1).
A. Spira, P. Marx, B. Patterson, J. Mahoney, R. Koup, Steven Wolinsky, D. Ho   +6 more
semanticscholar   +1 more source

Antibiotic Minocycline Prevents Respiratory Syncytial Virus Infection

Viruses, 2019
Treatment drugs, besides their specific activity, often have multiple effects on the body. The undesired effect of the drug may be repurposed as therapeutics, saving significant investigative time and effort.
Swapnil S. Bawage, Pooja M. Tiwari, Shreekumar Pillai, Vida A. Dennis, Shree R. Singh   +4 more
doaj   +1 more source

Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]

, 1988
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H., Hood, Leroy E., Jameson, Bradford A., Kappes, John C., Kent, Stephen B. H., Lee, Shei-Wen, Morrow, Casey D., Shaw, George M.   +7 more
core  

Impact of Recombinant VSV-HIV Prime, DNA-Boost Vaccine Candidates on Immunogenicity and Viremia on SHIV-Infected Rhesus Macaques

Vaccines
Currently, no effective vaccine to prevent human immunodeficiency virus (HIV) infection is available, and various platforms are being examined. The vesicular stomatitis virus (VSV) vaccine vehicle can induce robust humoral and cell-mediated immune ...
Alice Berger, Jannie Pedersen, Monika M. Kowatsch, Florine Scholte, Marc-Alexandre Lafrance, Hiva Azizi, Yue Li, Alejandro Gomez, Matthew Wade, Hugues Fausther-Bovendo, Marc-Antoine de La Vega, Joseph Jelinski, George Babuadze, Marie-Edith Nepveu-Traversy, Claude Lamarre, Trina Racine, Chil-Yong Kang, Bruno Gaillet, Alain Garnier, Rénald Gilbert, Amine Kamen, Xiao-Jian Yao, Keith R. Fowke, Eric Arts, Gary Kobinger   +24 more
doaj   +1 more source

Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor

Viruses, 2015
The Nef protein is an accessory gene product encoded by human immunodeficiency virus types 1 and 2 (HIV-1/-2) and simian immunodeficiency virus (SIV) that boosts virus replication in the infected host and accelerates disease progression. Unlike the HIV-1
Oliver T. Fackler
doaj   +1 more source

The hope for an HIV vaccine based on induction of CD8+ T lymphocytes: a review

Memorias do Instituto Oswaldo Cruz, 2008
The only long-term and cost-effective solution to the human immunodeficiency virus (HIV) epidemic in the developing world is a vaccine that prevents individuals from becoming infected or, once infected, from passing the virus on to others.
David I Watkins
doaj   +1 more source

Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. [PDF]

, 2020
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells.
Amara, Rama R, Beck, Zoltan, Dinasarapu, Ashok R, Elizaldi, Sonny R, Foehl, David H, Forthal, Donald N, Gach, Johannes S, Iyer, Smita S, Kozlowski, Pamela A, LaBranche, Celia C, Lakshmanappa, Yashavanth Shaan, Matyas, Gary R, Nguyen, Nancy K, Rane, Niharika N, Rao, Mangala, Reimann, Keith A, Schmidt, Brian A, Shen, Xiaoying, Tomaras, Georgia D, Trinh, Hung V, Verma, Anil, Walter, Korey A   +21 more
core  

Isolation of a new HIV-2 group in the US

Retrovirology, 2008
Human immunodeficiency virus type 2 (HIV-2) emerged following cross-species transmission of simian immunodeficiency virus (SIV) from sooty mangabeys to humans several decades ago. The epidemic groups of HIV-2 have been established in the human population
Gautam Aarti, Gautam Rajeev, Austin Louise, Shah Urvi, de Lame Valéry, Christian Deanna, Smith Stephen M, Apetrei Cristian, Marx Preston A   +8 more
doaj   +1 more source

Genital tract sequestration of SIV following acute infection. [PDF]

PLoS Pathogens, 2011
We characterized the evolution of simian immunodeficiency virus (SIV) in the male genital tract by examining blood- and semen-associated virus from experimentally and sham vaccinated rhesus monkeys during primary infection.
James B Whitney, Peter T Hraber, Corinne Luedemann, Elena E Giorgi, Marcus G Daniels, Tanmoy Bhattacharya, Srinivas S Rao, John R Mascola, Gary J Nabel, Bette T Korber, Norman L Letvin   +10 more
doaj   +1 more source