Results 11 to 20 of about 89 (88)
Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections [PDF]
Journal of Virology, 1998 ABSTRACTCharacterization of virus-specific immune responses to human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) is important to understanding the early virus-host interactions that may determine the course of virus infection and disease.
Ronald C. Montelaro +5 more
openaire +3 more sources
Susceptibilities of Simian Immunodeficiency Virus to Protease Inhibitors [PDF]
Antimicrobial Agents and Chemotherapy, 2003 ABSTRACT We used a focal infectivity assay with HeLa H1-JC.37 cells to directly compare susceptibilities of simian immunodeficiency virus (SIV) and human immunodeficiency virus type 1 (HIV-1) to protease inhibitors. SIVmac239 was inhibited by indinavir, saquinavir, and ritonavir, with 50% effective concentrations (means ± standard deviations)
Joanne Higgins +3 more
openaire +3 more sources
physica status solidi (a), EarlyView.Herein, C, N, and Ca concentration images in dry porcine intestine are used to determine trace element concentrations ex vivo. Physiologically relevant concentrations in biological tissue, in the in vivo, state are of the order of μmol L−1 and mmol L−1.
Harry J. Whitlow +13 more
wiley +1 more source
Organoid Models to Study Human Infectious Diseases
Cell Proliferation, EarlyView.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
The nef gene of simian immunodeficiency virus SIVmac1A11 [PDF]
Journal of Virology, 1992 The role of the simian immunodeficiency virus (SIV) nef gene in viral replication was investigated in several tissue culture systems. SIVmac1A11 is a molecularly cloned virus which replicates in both peripheral blood mononuclear cells (PBMC) and macrophages, although no disease is observed in infected rhesus macaques.
Phillip A. Padrid +4 more
openaire +2 more sources
American Journal of Primatology, Volume 87, Issue 6, June 2025.Data indicate that, across 3 years, significant elevations in urinary norepinephrine result from housing relocations compared to baseline (Time 1). ABSTRACT In captive primate facilities, relocations—moves, within the facility, from one cage to another—can be common events. On the one hand, relocations are generally regarded as relatively benign events,
John P. Capitanio +4 more
wiley +1 more source
Simian Immunodeficiency Virus Infection in Neonatal Macaques [PDF]
Journal of Virology, 2003 ABSTRACTChildren with human immunodeficiency virus infection often have higher viral loads and progress to AIDS more rapidly than adults. Since the intestinal tract is a major site of early viral replication and CD4+T-cell depletion in adults, we examined the effects of simian immunodeficiency virus (SIV) on both peripheral and intestinal lymphocytes ...
Ivona Pandrea +5 more
openaire +3 more sources
Land Use Change and Infectious Disease Emergence
Reviews of Geophysics, Volume 63, Issue 2, June 2025.Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli +6 more
wiley +1 more source
Aggregate, Volume 6, Issue 5, May 2025.Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai +6 more
wiley +1 more source
Structure of simian immunodeficiency virus regulatory genes. [PDF]
Proceedings of the National Academy of Sciences, 1989 Three full-length cDNA clones were obtained from cells infected with the simian immunodeficiency virus (SIV) isolated from captive macaques (SIVMAC). Nucleotide sequence analyses suggested that these represented mRNA for the SIV MAC genes tat, rev (formerly, art/trs), and nef (formerly, 3'orf).
Sandra Colombini +5 more
openaire +3 more sources