Results 41 to 50 of about 218,831 (262)

Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

Journal of Experimental Medicine, 1999
To determine the role of CD8+ T cells in controlling simian immunodeficiency virus (SIV) replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 monoclonal antibody, OKT8F. There was on average a 99.9% reduction of
Xia Jin, Daniel E. Bauer, Sarah Tuttleton, S. Lewin, A. Gettie, J. Blanchard, C. Irwin, J. Safrit, J. Mittler, L. Weinberger, L. Kostrikis, Linqi Zhang, A. Perelson, D. Ho   +13 more
semanticscholar   +1 more source

Simian immunodeficiency virus infection in wild-caught chimpanzees from Cameroon [PDF]

, 2005
Simian immunodeficiency viruses (SIVcpz) infecting chimpanzees (Pan troglodytes) in west central Africa are the closest relatives to all major variants of human immunodeficiency virus type 1 ([HIV-1]; groups M, N and O), and have thus been implicated as ...
Ayouba, A, Bailes, E, Barre-Sinoussi, F, Foupouapouognigni, Y F, Hahn, B H, Kfutwah, A, Muller-Trutwin, M C, Mundy, N I, Nerrienet, E, Njinku, B, Santiago, M L, Sharp, P M, Shaw, G M   +12 more
core   +2 more sources

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques

Journal of Virology, 2016
Despite the success of combined antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains a lifelong infection because of latent viral reservoirs in infected patients.
Claudia R. Avalos, Sarah L. Price, Ellen R. Forsyth, Julia N. Pin, E. Shirk, B. Bullock, S. Queen, Ming Li, Dane D. Gellerup, Shelby L. O’Connor, M. Zink, J. Mankowski, L. Gama, J. Clements   +13 more
semanticscholar   +1 more source

Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]

, 2015
Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric, Biffoni, Mauro, Chung, Hye Kyung, Farrell, Nicholas, Labranche, Celia, Lewis, Mark G., Montefiori, David, Nickel, Gabrielle, Pal, Ranajit, PALAMARA, ANNA TERESA, Robert Guroff, Marjorie, Sacha, Jonah B., Savarino, Andrea, Shytaj, Iart Luca, Vargas Inchaustegui, Diego   +14 more
core   +2 more sources

Development of a human leukocyte antigen-based HIV vaccine [version 1; referees: 2 approved]

F1000Research, 2018
Human immunodeficiency virus (HIV) carries abundant human cell proteins, particularly human leukocyte antigen (HLA) molecules when the virus leaves host cells.
Yufei Wang
doaj   +1 more source

Screening donors for xenotransplantation: The potential for xenozoonoses [PDF]

, 1994
Xenotransplantation is a potential solution to the current donor shortage for solid organ transplantation. The transmission of infectious agents from donor organs or bone marrow to the recipient is a well-recognized phenomenon following ...
Kahleen, B, Kalter, S, McMichael, JP, Michaels, MG, Peters, RL, Simmons, RL, Starzl, TE   +6 more
core   +1 more source

Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections [PDF]

Journal of Virology, 1998
ABSTRACTCharacterization of virus-specific immune responses to human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) is important to understanding the early virus-host interactions that may determine the course of virus infection and disease.
K S, Cole, M, Murphey-Corb, O, Narayan, S V, Joag, G M, Shaw, R C, Montelaro   +5 more
openaire   +2 more sources

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ, Dandekar, S, Gaulke, CA, Glavan, TW, Goulart, LR, Hirao, LA, Jiang, G, Raffatellu, M, Sankaran-Walters, S, Santos Rocha, C   +9 more
core   +2 more sources

A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy. [PDF]

PLoS ONE, 2009
Herpes simplex virus type-2 (HSV-2) infection enhances the transmission and acquisition of human immunodeficiency virus (HIV). This occurs in symptomatic and asymptomatic stages of HSV-2 infection, suggesting that obvious herpetic lesions are not ...
Federica Crostarosa, Meropi Aravantinou, Onome J Akpogheneta, Edith Jasny, Andrew Shaw, Jessica Kenney, Michael Piatak, Jeffrey D Lifson, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M Zydowsky, James Blanchard, Agegnehu Gettie, Melissa Robbiani   +14 more
doaj   +1 more source

The role of the chemokine receptor CXCR4 in infection with feline immunodeficiency virus [PDF]

, 1999
Infection with feline immunodeficiency virus (FIV) leads to the development of a disease state similar to AIDS in man. Recent studies have identified the chemokine receptor CXCR4 as the major receptor for cell culture-adapted strains of FIV, suggesting ...
Ackley C. D., Amara A., Barr M. C., Bleul C. C., Boyer V., Brelot A., Brian J. Willett,, Brown E. W., Brunner D., Cao J., Choe H., de Jong J. J., Dean G. A., Donzella G. A., Doranz B. J., Dow S. W., Dubay J. W., Egberink H. F., Endo Y., Endres M. J., Feng Y., Hesselgesser J., Hill C. M., Ho D. D., Hosie M. J., Ikeda Y., Langley R. J., Lu Z. H., Margaret J. Hosie, Muster T., Norimine J., Novotney C., Oberlin E., Olmsted R. A., Pancino G., Parolin C., Poeschla E. M., Reeves J. D., Reeves J. D., Robinson W. E., Siebelink K. H. J., Speck R. F., Talbott R. L., Vahlenkamp T. W., Verschoor E. J., Wild C., Willett B. J., Willett B. J., Willett B. J., Willett B. J., Wu L.   +50 more
core   +1 more source