Results 11 to 20 of about 1,956 (160)
Cancer Reports, Volume 6, Issue 11, November 2023., 2023 Abstract Background Cancer is an outcome of various disrupted or dysregulated metabolic processes like apoptosis, growth, and self‐cell transformation. Human anatomy harbors trillions of microbes, and these microbes actively influence all kinds of human metabolic activities, including the human immune response.
Saksham Garg +3 more
wiley +1 more source
Regulation of Polyomavirus Transcription by Viral and Cellular Factors
Viruses, 2020 Polyomavirus infection is widespread in the human population. This family of viruses normally maintains latent infection within the host cell but can cause a range of human pathologies, especially in immunocompromised individuals.
June F. Yang, Jianxin You
doaj +1 more source
Journal of Comparative Neurology, Volume 531, Issue 13, Page 1276-1298, September 2023., 2023 Understanding the age‐associated incidence of natural CNS pathology in an animal model is critical to assess the safety of potential treatments for neurodegenerative disorders. We describe background and age‐related neuropathology in the St. Kitts African green monkey, a recognized translational model for neurodegenerative research, additionally ...
Tatiana M. Corey +5 more
wiley +1 more source
Strategies for immortalisation of amnion‐derived mesenchymal and epithelial cells
Cell Biology International, Volume 46, Issue 12, Page 1999-2008, December 2022., 2022 Abstract Mesenchymal (human amniotic mesenchymal stem cell [HAMSC]) and epithelial cells (human amnion epithelial cell [HAEC]) derived from human amniotic membranes possess characteristics of pluripotency. However, the pluripotency of HAMSC and HAEC are sustained only for a finite period.
Aneesa Ansari +2 more
wiley +1 more source
Current Protocols, Volume 2, Issue 5, May 2022., 2022 Abstract Yeast‐based interaction assays to determine protein‐protein and protein‐nucleic acid interactions commonly rely on the reconstitution of chimeric transcription factors that activate the expression of target reporter genes. The enzyme β‐galactosidase (β‐gal), coded by the LacZ gene of Escherichia coli, is a widely used reporter in yeast systems,
Laura Trimborn +2 more
wiley +1 more source
Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters [PDF]
, 2014 Shaojie Zhang, Vojtech Sroller, Preeti Zanwar, Steven J. Halvorson, Nadim J. Ajami, Corey W. Hecksel, Jody L. Swain, Connie Wong, Janet S. Butel, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States
Ajami, Nadim J. +10 more
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The Dawn of Plant Molecular Biology: How Three Key Methodologies Paved the Way
Current Protocols, Volume 2, Issue 4, April 2022., 2022 Abstract The adoption of Arabidopsis thaliana in the 1980s as a universal plant model finally enabled researchers to adopt and take full advantage of the molecular biology tools and methods developed in the bacterial and animal fields since the early 1970s.
Marc Somssich
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Cell transformation of established human cell line induced by SV-40 DNA [PDF]
, 1966 In the present experiment, it has been noted that clonizing epithelial-like cells of the intestine 407 were more susceptible to SV-40 virus than normal fibroblasts in primary human cell cultures.
Grace, James T., Kimoto, Tetsuo
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Current Protocols, Volume 1, Issue 12, December 2021., 2021 Abstract Human artificial chromosomes (HACs) are gene delivery vectors that have been used for decades for gene functional studies. HACs have several advantages over viral‐based gene transfer systems, including stable episomal maintenance in a single copy in the cell and the ability to carry up to megabase‐sized genomic DNA segments. We have previously
Nicholas C. O. Lee +3 more
wiley +1 more source
Oncogenic properties of nucleic acid derived from SV-40 virus [PDF]
, 1966 The present report describes the findings on the infectivity of DNA partially purified from SV-40 which was propagated in the monkey kidney cells (BSC-1) in vitro and the importance of nucleic acids as oncogenic factors, particularly the induction of ...
Grace, James T., Kimoto, Tetsuo
core +1 more source