Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]
, 2015 Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric +14 more
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Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges [PDF]
, 2005 BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis.
Feinberg, Mark B +3 more
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Simian Virus 40 Infection of Humans [PDF]
Journal of Virology, 2003 Since its discovery, simian virus 40 (SV40) has been one of the most intensely studied animal viruses. The molecular biology of SV40 has led to seminal discoveries in the fields of transcription, DNA replication, and oncogenic transformation ([19][1]).
Robert L, Garcea, Michael J, Imperiale
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EFFICIENT PROPAGATION OF ARCHETYPE JC POLYOMAVIRUS IN COS-7 CELLS: EVALUATION OF REARRANGEMENTS WITHIN NCCR STRUCTURAL ORGANIZATION DURING TRANSFECTION. [PDF]
, 2017 John Cunningham virus (JCPyV) is an ubiqui-tous human pathogen that causes disease in immunocom-promised patients. The JCPyV genome is composed of an early region and a late region, which are physically sepa-rated by the ...
Anzivino, Elena +7 more
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Transforming functions of Simian Virus 40 [PDF]
Oncogene, 2001 Oncogene (2001) 20, 7899–7907.Keywords: SV40; tumor suppressor; chaperone; tumorvirusIntroductionCancer is thought to progress through multiple stageswith each stage giving rise to cells showing increasedmalignant characteristics. Progression through thesestages is driven by genetic events such as mutations intumor suppressor genes or oncogenes, or the
M T, Sáenz-Robles +2 more
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Salt‐stable association of simian virus 40 capsid with simian virus 40 DNA
FEBS Letters, 1985 In 8 M CsCl, a fraction of the wild‐type previrions and tsB228 nucleoprotein complexes lose their core histones but retain their capsid. These histone‐depleted complexes apear in the electron microscope as a protein shell attached to supercoiled DNA.
Blasquez, Veronica, Bina, Minou
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Relationship between molecular length and biological activity of SV40 DNA [PDF]
, 1970 The correlation of infectivity to the length of SV 40 DNA by dilute and undiluted passage was described. DNA was extracted from purified virions by Marmur's method, and propagation of virus was done using VERO cells.
Oda, Takuzo +2 more
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Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection. [PDF]
, 2016 HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined.
Dandekar, Satya +6 more
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Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses [PDF]
, 2017 G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter.
A Ayouba +67 more
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Airborne Stability of Simian Virus 40 [PDF]
Applied Microbiology, 1973 The influence of relative humidity on the airborne survival of simian virus 40 (SV40) was studied by allowing virus aerosols to age in rotating drums at 21 or 32 C and at a relative humidity (RH) value ranging from 22 to 88%. Airborne SV40 virus was stable at every RH tested at 21 C, but aerosols maintained at 32 C were inactivated within 60 min at mid-
T G, Akers, C M, Prato, E J, Dubovi
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