Results 41 to 50 of about 59,879 (217)

Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]

open access: yes, 2011
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F.   +43 more
core   +1 more source

Role of endosomes in simian virus 40 entry and infection. [PDF]

open access: yesJ Virol, 2011
After binding to its cell surface receptor ganglioside GM1, simian virus 40 (SV40) is endocytosed by lipid raft-mediated endocytosis and slowly transported to the endoplasmic reticulum, where partial uncoating occurs.
Engel S   +6 more
europepmc   +2 more sources

Human mesotheliomas contain the simian virus-40 regulatory region and large tumor antigen DNA sequences [PDF]

open access: yes, 1998
Background: A cohort (20%) of patients with mesothelioma will not have an exposure to asbestos. Recently, a DNA tumor virus (simian virus 40) has been shown to cause hamster mesotheliomas; we previously described simian virus 40–like DNA amino terminus ...
Rizzo, Paola   +6 more
core   +1 more source

Modification of simian virus 40 protein A [PDF]

open access: yesJournal of Virology, 1977
The A protein of simian virus 40 is phosphorylated in both productive and transforming infection. The phosphorylated amino acid has been identified as serine and has been localized in a single tryptic peptide of the protein. Because the A protein synthesized in infection by A mutants is phosphorylated to the same extent and in the same peptide as in ...
P, Tegtmeyer, K, Rundell, J K, Collins
openaire   +2 more sources

No Implication of Simian virus 40 in pathogenesis of Malignant Pleural Mesothelioma in Slovenia [PDF]

open access: yes, 2010
Background and aim Malignant mesothelioma is predominantly caused by asbestos exposure, although the association of Simian virus 40 in its pathogenesis is currently still under debate. Simian virus 40, a DNA rhesus monkey virus with oncogenic properties,
Izidor Kern, Andrej Cör, Julija Hmeljak
core   +1 more source

HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers [PDF]

open access: yes, 2009
Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment ...
C. J. Brumme   +21 more
core   +2 more sources

SV40 Polyomavirus Activates the Ras-MAPK Signaling Pathway for Vacuolization, Cell Death, and Virus Release

open access: yesViruses, 2020
Polyomaviruses are a family of small, non-enveloped DNA viruses that can cause severe disease in immunosuppressed individuals. Studies with SV40, a well-studied model polyomavirus, have revealed the role of host proteins in polyomavirus entry and ...
Nasim Motamedi   +4 more
doaj   +1 more source

Inactivation of Polyomavirus SV40 as Surrogate for Human Papillomaviruses by Chemical Disinfectants

open access: yesViruses, 2021
Human papillomaviruses (HPV) are non-enveloped DNA viruses infecting cutaneous and mucosal squamous epithelia. Sexually transmitted HPV-types that are carcinogenic to humans such as HPV16 can induce cervical and other anogenital cancers.
Martin Hufbauer   +5 more
doaj   +1 more source

Simian Virus 40 Infection of Humans [PDF]

open access: yesJournal of Virology, 2003
Since its discovery, simian virus 40 (SV40) has been one of the most intensely studied animal viruses. The molecular biology of SV40 has led to seminal discoveries in the fields of transcription, DNA replication, and oncogenic transformation ([19][1]).
Robert L, Garcea, Michael J, Imperiale
openaire   +2 more sources

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

open access: yesAdvanced Science, EarlyView.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble   +9 more
wiley   +1 more source

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