Results 51 to 60 of about 4,147,981 (191)

Inactivation of Polyomavirus SV40 as Surrogate for Human Papillomaviruses by Chemical Disinfectants

Viruses, 2021
Human papillomaviruses (HPV) are non-enveloped DNA viruses infecting cutaneous and mucosal squamous epithelia. Sexually transmitted HPV-types that are carcinogenic to humans such as HPV16 can induce cervical and other anogenital cancers.
Martin Hufbauer, Ulrike Wieland, Jürgen Gebel, Jochen Steinmann, Baki Akgül, Maren Eggers   +5 more
doaj   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Transforming functions of Simian Virus 40 [PDF]

Oncogene, 2001
Oncogene (2001) 20, 7899–7907.Keywords: SV40; tumor suppressor; chaperone; tumorvirusIntroductionCancer is thought to progress through multiple stageswith each stage giving rise to cells showing increasedmalignant characteristics. Progression through thesestages is driven by genetic events such as mutations intumor suppressor genes or oncogenes, or the
M T, Sáenz-Robles, C S, Sullivan, J M, Pipas   +2 more
openaire   +2 more sources

New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma

Frontiers in Oncology, 2018
Malignant pleural mesothelioma (MPM) is a rare, but severe form of cancer, with an incidence that varies significantly within and among different countries around the world.
Marika Rossini, Paola Rizzo, Ilaria Bononi, Anthony Clementz, Roberto Ferrari, Roberto Ferrari, Fernanda Martini, Mauro G. Tognon   +7 more
doaj   +1 more source

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

Biotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing, Tomoki Igi, Daniel Strauss   +2 more
wiley   +1 more source

Structural Polypeptides of Simian Virus 40 [PDF]

Journal of Virology, 1971
To determine the number and molecular weights of the structural polypeptides of simian virus 40, we have analyzed purified virus by electrophoresis on 14% polyacrylamide gels containing sodium dodecyl sulfate. Full virus purified by several different methods showed six distinct bands with molecular weights of approximately 43,000 (VP1, containing 70 ...
M K, Estes, E S, Huang, J S, Pagano
openaire   +2 more sources

Transformation of B Lymphocytes by SV40, a small DNA tumor virus [PDF]

, 2012
For decades we have assessed the risk to humans by the monkey virus SV40, through studies in animal models and humans. While there is increase in the accumulation of opinions over its DNA sequence prevalence in certain human cancers, especially non ...
Alaribe, Franca Nneka
core  

Transcription and Replication Result in Distinct Epigenetic Marks Following Repression of Early Gene Expression

Frontiers in Genetics, 2013
Simian Virus 40 (SV40) early transcription is repressed when the product of early transcription, T-antigen, binds to its cognate regulatory sequence, Site I, in the promoter of the SV40 minichromosome.
Les eKallestad, Emily eWoods, Kendra eChristensen, Amanda eGefroh, Lata eBalakrishnan, Barry eMilavetz   +5 more
doaj   +1 more source

Simian immunodeficiency virus (SIV) from sun-tailed monkeys (Cercopithecus solatus):Evidence for host-dependent evolution of SIV within the C. lhoesti superspecies [PDF]

, 1999
Recently we reported the characterization of simian immunodeficiency virus (SIVlhoest) from a central African l'hoest monkey (Cercopithecus lhoesti lhoesti) that revealed a distant relationship to SIV isolated from a mandrill (SIVmnd). The present report
Gautier, JP, Kurth, Reinhard, Gautier-Hion, A, Goeken, R, Sharp, Paul M, Norley, Stephen G., Kurth, R, Beer, BE, Coulibaly, Cheik, Gautier-Hion, Annie, Bailes, Elizabeth, Dapolito, George, Sharp, Paul M., Bailes, E, Dapolito, G, Vallet, D, Coulibaly, C, Vallet, Dominique, Hirsch, VM, Hirsch, Vanessa M., Beer, Brigitte E, Norley, SG, Gautier, Jean-Pierre, Goeken, Robert   +23 more
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