Results 71 to 80 of about 94,849 (208)

Structural Polypeptides of Simian Virus 40 [PDF]

Journal of Virology, 1971
To determine the number and molecular weights of the structural polypeptides of simian virus 40, we have analyzed purified virus by electrophoresis on 14% polyacrylamide gels containing sodium dodecyl sulfate. Full virus purified by several different methods showed six distinct bands with molecular weights of approximately 43,000 (VP1, containing 70 ...
M K, Estes, E S, Huang, J S, Pagano
openaire   +2 more sources

SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes

Biotechnology Reports, 2015
The icosahedral capsid structure of simian virus 40 (diameter, 45 nm) consists of 72 pentameric subunits, with each subunit formed by five VP1 molecules. Electron microscopy, immuno-gold labeling, and ζ-potential analysis showed that purified recombinant
Masaaki Kawano, Koji Doi, Hajime Fukuda, Yoshinori Kita, Kensuke Imai, Takamasa Inoue, Teruya Enomoto, Masanori Matsui, Mamoru Hatakeyama, Yuki Yamaguchi, Hiroshi Handa   +10 more
doaj   +1 more source

The Research Progress on Immortalization of Human B Cells

Microorganisms, 2023
Human B cell immortalization that maintains the constant growth characteristics and antibody expression of B cells in vitro is very critical for the development of antibody drugs and products for the diagnosis and bio-therapeutics of human diseases ...
Huiting Xu, Xinxin Xiang, Weizhe Ding, Wei Dong, Yihong Hu   +4 more
doaj   +1 more source

Increased concentration of an apparently identical cellular protein in cells transformed by either Abelson murine leukemia virus or other transforming agents [PDF]

, 1981
Abelson murine leukemia virus (A-MuLV)-transformed cells, simian virus 40 (SV40)-transformed cells, and chemically transformed cells all have increased levels of a 50,000-molecular-weight host cell protein.
Baltimore, David, Boss, Michael A., Rotter, Varda   +2 more
core   +1 more source

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ, Dandekar, S, Gaulke, CA, Glavan, TW, Goulart, LR, Hirao, LA, Jiang, G, Raffatellu, M, Sankaran-Walters, S, Santos Rocha, C   +9 more
core   +2 more sources

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad, Narges Eslami, Kaveh Gharaei Nejad, Atefeh Zamani Kermanshahi, Hossein Bannazadeh Baghi   +4 more
wiley   +1 more source

Simian virus 40 and the human mesothelium [PDF]

Proceedings of the National Academy of Sciences, 2000
Potentially tumorigenic papovaviruses and adenoviruses stimulate host cell DNA synthesis. The induction of an S phase appears to be essential for the integration of the viral genome into host cell DNA. The induction of host cell proliferation is a secondary consequence. Under natural conditions, the risk of malignant growth is counteracted by the viral
openaire   +2 more sources

Selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40 [PDF]

Journal of Virology, 1985
Treatment of African green monkey kidney CV-1 cells with human alpha interferons before infection with simian virus 40 (SV40) inhibited the accumulation of SV40 mRNAs and SV40 T-antigen (Tag). This inhibition persisted as long as the interferons were present in the medium.
M A, García-Blanco, P K, Ghosh, B M, Jayaram, S, Ivory, P, Lebowitz, P, Lengyel   +5 more
openaire   +2 more sources

A Novel, Broad-Acting Peptide Inhibitor of Double-Stranded DNA Virus Gene Expression and Replication

Frontiers in Microbiology, 2020
Viral infections are a global disease burden with only a limited number of antiviral agents available. Due to newly emerging viral pathogens and increasing occurrence of drug resistance, there is a continuous need for additional therapeutic options ...
Zsolt Ruzsics, Zsolt Ruzsics, Zsolt Ruzsics, Katja Hoffmann, Katja Hoffmann, André Riedl, André Riedl, Adalbert Krawczyk, Adalbert Krawczyk, Marek Widera, Marek Widera, Helene Sertznig, Leonie Schipper, Valeria Kapper-Falcone, Valeria Kapper-Falcone, Valeria Kapper-Falcone, Monika Debreczeny, Wolfgang Ernst, Reingard Grabherr, Hartmut Hengel, Hartmut Hengel, Hartmut Hengel, Hanna Harant   +22 more
doaj   +1 more source