Results 91 to 100 of about 4,147,981 (191)

Immortalization of Adipose‐Derived Stromal Cells From Japanese Black Cattle

Cell Biology International, Volume 50, Issue 8, August 2026.
ABSTRACT Adipose tissue plays a critical role in determining the characteristic palatability of Japanese Black cattle beef, including its distinctive aroma, tenderness, and flavor. These quality traits are closely associated with adipogenic differentiation and lipid metabolism; however, the underlying molecular mechanisms remain poorly understood ...
Rei Sasaki, Hanami Matsukura, Ryo Meguro, Lanlan Bai, Ken Sawai, Eriko Sugano, Hiroshi Tomita, Tohru Kiyono, Tomokazu Fukuda   +8 more
wiley   +1 more source

Contrasting Effects of HT‐2 Toxin Exposure and ZIP6 Knockdown on Chondrocyte Extracellular Matrix Metabolism

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
HT‐2 toxin triggers chondrocyte damage and matrix metabolism disorders in KBD via suppressing ZIP6. ZIP6 knockdown alleviates these dysfunctions through FoxO, cAMP and TNF pathways, clarifying the molecular mechanism of cartilage injury. ABSTRACT Kashin‐Beck disease (KBD) is a chronic, endemic osteoarticular disorder associated with T‐2 toxin exposure,
Yang Liu, Yu Zhang, Ruitian Huang, Lulu Bai, Lian Liu, Chaowei Wang, Yirong Qin, Hui Wang, Xiong Guo, Xi Wang, Yujie Ning   +10 more
wiley   +1 more source

Inhibition of simian virus 40 DNA replication by human papilloma virus DNA sequences.

, 1993
Inhibition of simian virus 40 DNA replication by human papilloma virus DNA ...
Daniel Christopher. Alter (7990451)
core   +6 more sources

Fra-1 governs cell migration via modulation of CD44 expression in human mesotheliomas

Molecular Cancer, 2007
Silencing of Fra-1, a component of the dimeric transcription factor, activator protein-1 (AP-1), inhibits mRNA expression of c-met and cd44 in rat mesothelioma cells and is causally linked to maintenance of the transformed phenotype.
Pass Harvey, Blumen Steven R, Ramos-Nino Maria E, Mossman Brooke T   +3 more
doaj   +1 more source

Successful Retroviral Gene Transfer of Simian Virus 40 T Antigen and Herpes Simplex Virus-Thymidine Kinase into Human Hepatocytes

Cell Transplantation, 2001
Current clinical reports have indicated that hepatocyte transplantation (HTX) could be used in patients with liver failure and in children with liver-based metabolic diseases. One of the major limiting factors of HTX is a serious shortage of donor livers
Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Karen A. Westerman, Takamasa Watanabe, Toshihisa Matsumura, Toshinori Totsugawa, Toshiyoshi Fujiwara, Philippe Leboulch, Noriaki Tanaka   +8 more
doaj   +1 more source

Checkpoint inhibitor blockade and epigenetic reprogrammability in CD8 T-cell activation and exhaustion

Therapeutic Advances in Vaccines and Immunotherapy, 2020
CD8 + T-cell exhaustion is a dysfunctional state that is regulated through the expression of inhibitory checkpoint receptor genes including the cytotoxic T-lymphocyte–associated antigen 4, programmed death 1, and DNA methylation of effector genes ...
José Belizário, Maria Fernanda Destro Rodrigues   +1 more
doaj   +1 more source

Polyomaviruses and the risk of oral cancer: a systematic review and meta-analysis

BMC Oral Health
Objectives Oral cancer (OC) is the most common malignant tumor of the head and neck (HN) and ranks 16th among the most frequently diagnosed cancers worldwide.
Tahoora Mousavi, Fatemeh Shokoohy, Mahmood Moosazadeh   +2 more
doaj   +1 more source

Treatment of Surgically Induced Acute Liver Failure with Transplantation of Highly Differentiated Immortalized Human Hepatocytes

Cell Transplantation, 2000
Primary human hepatocytes are an ideal source of hepatic function in bioartficial liver (BAL), but the shortage of human livers available for hepatocyte isolation limits this modality.
Naoya Kobayashi M.D., Ph.D., Masahiro Miyazaki, Kenichi Fukaya, Yusuke Inoue, Masakiyo Sakaguchi, Hirofumi Noguchi, Toshihisa Matsumura, Takamasa Watanabe, Toshinori Totsugawa, Noriaki Tanaka, Masayoshi Namba M.D.   +10 more
doaj   +1 more source

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection [PDF]

, 2013
Persistent production of type I interferon (IFN) by activated plasmacytoid dendritic cells (pDC) is a leading model to explain chronic immune activation in human immunodeficiency virus (HIV) infection but direct evidence for this is lacking.
Simon C Watkins, Normolle, D, Kader, M, Elizabeth R Wonderlich, Guiducci, C, Smith, Amanda P., Watkins, SC, Amanda P. Smith (437248), Normolle, Daniel, Watkins Simon C., Franck J. Barrat (437251), Smith Amanda P., Simon M Barratt-Boyes, Daniel Normolle, Daniel Normolle (437250), Barrat Franck J., Simon M. Barratt-Boyes (264203), Normolle Daniel, Wonderlich Elizabeth R., Franck J Barrat, Barratt-Boyes Simon M., Guiducci, Cristiana, Barrat, Franck J., Kader, Muhamuda, Guiducci Cristiana, Wonderlich, ER, Cristiana Guiducci, Barrat, FJ, Watkins, Simon C., Amanda P Smith, Barratt-Boyes, SM, Muhamuda Kader, Smith, AP, Wonderlich, Elizabeth R., Cristiana Guiducci (437249), Simon C. Watkins (39900), Barratt-Boyes, Simon M., Muhamuda Kader (437247), Elizabeth R. Wonderlich (270792), Kader Muhamuda   +39 more
core   +2 more sources

Simian virus 40 and human malignancy

BMJ, 1998
The introduction of the Salk parenteral vaccine in the mid-1950s led to a dramatic decline in the incidence of poliomyelitis. By 1961, the majority of young adults in Britain and America had been immunised and the numbers of reported cases of poliomyelitis had fallen from 8000 a year to 100 a year.1 At that point in the mass immunisation programme, a ...
openaire   +3 more sources