Results 61 to 70 of about 4,147,981 (191)

Mesothelioma mortality in Europe: impact of asbestos consumption and simian virus 40

Orphanet Journal of Rare Diseases, 2006
Background It is well established that asbestos is the most important cause of mesothelioma. The role of simian virus 40 (SV40) in mesothelioma development, on the other hand, remains controversial.
Rehak Peter, Krippl Peter, Radl Roman, Weinhaeusel Andreas, Clar Heimo, Leithner Andreas, Leithner Katharina, Windhager Reinhard, Haas Oskar A, Olschewski Horst   +9 more
doaj   +1 more source

Simian immunodeficiency virus and storage buffer: Field-friendly preservation methods for RNA viral detection in primate feces

mSphere, 2023
Wild non-human primates carry many types of RNA viruses, including simian immunodeficiency virus (SIV), simian foamy virus, simian T-cell leukemia virus, and hepatitis C virus.
Tessa H. C. Wilde, Rajni Kant Shukla, Christopher Madden, Yael Vodovotz, Amit Sharma, W. Scott McGraw, Vanessa L. Hale   +6 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Inzidenz von Simian-Virus-40-ähnlichen Sequenzen in ependymalen Tumoren

, 2005
Von 1955 bis 1963 erhielten Millionen von Kindern und Erwachsenen mit Simian-Virus-40-kontaminierten Impfstoff zur Poliomyelitis-Immunisierung. Das onkogene Potenzial dieses Polyomavirus wurde entdeckt, nachdem neugeborene Hamster nach intrazerebraler ...
Reuther, Frank Joachim
core   +1 more source

Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses

mBio, 2017
Inflammatory responses, while essential for pathogen clearance, can also be deleterious to the host. Chemical inhibition of topoisomerase 1 (Top1) by low-dose camptothecin (CPT) can suppress transcriptional induction of antiviral and inflammatory genes ...
Geneviève Pépin, Charlotte Nejad, Jonathan Ferrand, Belinda J. Thomas, H. James Stunden, Elaine Sanij, Chwan-Hong Foo, Cameron R. Stewart, Jason E. Cain, Philip G. Bardin, Bryan R. G. Williams, Michael P. Gantier   +11 more
doaj   +1 more source

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

Transfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira, Anna S. Nishyia, Jerenice E. Ferreira, Claudia Di Lorenzo Oliveira, Cesar de Almeida‐Neto, Tila Fanciani, Katia C. Dantas, Juliana Derriga, Silvia Petrossi Gallo Polato, Nanci Salles, Vanderson Rocha, Alfredo Mendrone‐Junior   +11 more
wiley   +1 more source

Simian virus 40 and the human mesothelium [PDF]

Proceedings of the National Academy of Sciences, 2000
Potentially tumorigenic papovaviruses and adenoviruses stimulate host cell DNA synthesis. The induction of an S phase appears to be essential for the integration of the viral genome into host cell DNA. The induction of host cell proliferation is a secondary consequence. Under natural conditions, the risk of malignant growth is counteracted by the viral
openaire   +2 more sources

Selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40 [PDF]

Journal of Virology, 1985
Treatment of African green monkey kidney CV-1 cells with human alpha interferons before infection with simian virus 40 (SV40) inhibited the accumulation of SV40 mRNAs and SV40 T-antigen (Tag). This inhibition persisted as long as the interferons were present in the medium.
M A, García-Blanco, P K, Ghosh, B M, Jayaram, S, Ivory, P, Lebowitz, P, Lengyel   +5 more
openaire   +2 more sources

HIV incidence and correlates of incident infection among Brazilian blood donors following adoption of individual donor assessment

Vox Sanguinis, EarlyView.
Abstract Background and Objectives In 2020, Brazil implemented individual donor assessment (IDA), expanding eligibility to include individuals previously deferred, such as men who have sex with men (MSM). We assessed human immunodeficiency virus (HIV) incidence and correlates of incident infection among blood donors following this policy change ...
Renata Buccheri, Eduard Grebe, Donald E. Warden, Carolina Miranda, Ligia Capuani, Cecilia S. Alencar, Luiz Amorim, Cesar de Almeida‐Neto, Maisa Ribeiro, Paula Loureiro, Nelson Fraiji, Clara Di Germanio, Leilani Montalvo, Jennifer Leddy, Mars Stone, Ester C. Sabino, Brian Custer, the Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P)   +17 more
wiley   +1 more source

SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes

Biotechnology Reports, 2015
The icosahedral capsid structure of simian virus 40 (diameter, 45 nm) consists of 72 pentameric subunits, with each subunit formed by five VP1 molecules. Electron microscopy, immuno-gold labeling, and ζ-potential analysis showed that purified recombinant
Masaaki Kawano, Koji Doi, Hajime Fukuda, Yoshinori Kita, Kensuke Imai, Takamasa Inoue, Teruya Enomoto, Masanori Matsui, Mamoru Hatakeyama, Yuki Yamaguchi, Hiroshi Handa   +10 more
doaj   +1 more source