Results 271 to 280 of about 4,594,222 (312)

Repetitive DNA sequences: Some considerations for simple sequence repeats

Computers & Chemistry, 1993
Abstract Three topics are treated in this paper: (1) can the polymorphism evident in the length of many simple sequence repeats (SSRs) or microsatellites be explained as a result of unequal mitotic crossing over? We conclude that although this mechanism may be a reasonable explanation for polymorphisms of minisatellite sequences, it is less ...
George I. Bell, David C. Torney
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Simple Sequence Repeat

2018
DNA markers are powerful tools for molecular breeding or checking the genetic homogeneity of F1 hybrid seeds. For the simple and fast approach to detect DNA polymorphisms, simple sequence repeats (SSRs), which are tandem repeats of short sequence motifs (mainly 1–6 bases), are powerful markers because of their codominant mode of inheritance, higher ...
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Complex and simple sequences in human repeated DNAs

Chromosoma, 1978
Highly repeated human DNA sequences were isolated by isopycnic centrifugation, or were eluted from gels after restriction enzyme cleavage. High molecular weight DNA peaks separable from the bulk of the DNA in a variety of gradients were shown to consist of very simple sequences characteristic of simple satellite DNAs; DNA fingerprint studies indicated ...
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Polymorphism revealed by simple sequence repeats

Trends in Plant Science, 1996
Simple sequence repeats (SSRs) are a group of repetitive DNA sequences that represent a significant portion of higher eukaryote genomes. They can serve as highly informative genetic markers, and in conjunction with the use of polymerase chain reaction (PCR) technology enable the detection of length variation.
Powell, W., Machray, G.C., Provan, Jim
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Some Probabilistic Results on the Nonrandomness of Simple Sequence Repeats in DNA Sequences

Bulletin of Mathematical Biology, 2006
Some probabilistic results on simple sequence repeats (SSRs) in DNA sequences are derived and used to quantify the nonrandomness of SSRs as an index of nonrandomness. The applicability of the index of nonrandomness is illustrated using several examples from the literature on selected human diseased genes.
Ndifon, Wilfred, Nkwanta, Asamoah, Hill, Dwayne   +2 more
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Conservation of a dinucleotide simple sequence repeat locus in sharks

Molecular Phylogenetics and Evolution, 2002
Recent studies indicate that the flanking region and repeat motif structure of conserved microsatellite loci are useful for phylogenetic inference. Most comparative studies of microsatellite loci involve relatively closely related species, however, primarily because primers developed for one species often amplify only related species.
Andrew P, Martin, Amanda T, Pardini, Leslie R, Noble, Catherine S, Jones   +3 more
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Evolution of Simple Sequence Repeats as Mutable Sites

2012
Because natural selection is commonly presumed to minimize mutation rates, the discovery of mutationally unstable simple sequence repeats (SSRs) in many functional genomic locations came as a surprise to many biologists. Whether such SSRs persist in spite of or because of their intrinsic mutability-whether they constitute a genetic burden or an ...
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Rapid Evolution of Simple Sequence Repeat Induced by Allopolyploidization

Journal of Molecular Evolution, 2009
Microsatellite evolution normally occurs in diploids. Until now, there has been a lack of direct experimental evidence for microsatellite evolution following allopolyploidization. In the present study, F(1) hybrids and newly synthesized allopolyploids were derived from Triticum aestivum Chinese Spring x Secale cereale Jinzhou-heimai.
Zongxiang, Tang, Shulan, Fu, Zhenglong, Ren, Yuting, Zou   +3 more
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Simple sequence repeats in proteins and their significance for network evolution

Gene, 2005
Only 5-6% of mammalian genomes are genes; the remainders are made up primarily of transposable elements and different types of simple sequence repeat (SSRs) (micro- and minisatellites and cryptic repeats), which tend to accumulate in organisms with larger genomes.
John M, Hancock, Michelle, Simon
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Simple sequence repeats as a source of quantitative genetic variation

Trends in Genetics, 1997
Most traits in biological populations appear to be under stabilizing selection, which acts to eliminate quantitative genetic variation. Yet, virtually all measured traits in biological populations continue to show significant quantitative genetic variation.
Y, Kashi, D, King, M, Soller
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