Results 41 to 50 of about 8,219 (147)

The landscape of viral associations in human cancers [PDF]

, 2020
Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik, Borozan, Ivan, Brewer, Daniel S, Cooper, Colin S, Desai, Nikita, Eils, Roland, Ferretti, Vincent, Grundhoff, Adam, Iskar, Murat, Lichter, Peter, Moch, Holger, PCAWG Consortium, PCAWG Pathogens, Sültmann, Holger, Zapatka, Marc   +14 more
core   +3 more sources

Corticosteroids for the common cold [PDF]

, 2015
BACKGROUND: The common cold is a frequent illness, which, although benign and self limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit.
Del Mar, Chris B., Glasziou, Paul P., Hayward, Gail, Heneghan, Carl J., Perera, Rafael, Thompson, Matthew J.   +5 more
core   +1 more source

Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]

, 2005
Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines, Ilarregui, Juan Martin, Rabinovich, Gabriel Adrián, Rubinstein, Natalia, Sanjuan, Norberto Aníbal, Toscano, Marta Alicia   +5 more
core   +1 more source

Metagenomic analysis of DNA viruses from posttransplant lymphoproliferative disorders

Cancer Medicine, Volume 8, Issue 3, Page 1013-1023, March 2019., 2019
We sequenced viral DNA from paraffin‐embedded tissues of PTLD and associated to clinical severity and outcomes. Certain EBV genes had higher proportions of nonsynonymous variants. Anellovirus tissue positivity associated with earlier patient death. Abstract Posttransplant lymphoproliferative disorders (PTLDs), 50%‐80% of which are strongly associated ...
Vikas R. Dharnidharka, Marianna B. Ruzinova, Chun‐Cheng Chen, Priyanka Parameswaran, Harry O'Gorman, Charles W. Goss, Hongjie Gu, Gregory A. Storch, Kristine Wylie   +8 more
wiley   +1 more source

Volatile Acid‐Solvent Evaporation (VASE): Molecularly Homogeneous Distribution of Acyclovir in a Bioerodable Polymer Matrix for Long‐Term Treatment of Herpes Simplex Virus‐1 Infections

Journal of Drug Delivery, Volume 2018, Issue 1, 2018., 2018
Treatment for herpes simplex virus‐1 and ‐2 (HSV‐1 and ‐2) patients who suffer from recurrent outbreaks consists of multiple daily doses of the antiviral drugs acyclovir (ACV), penciclovir, or their more orally bioavailable derivatives valacyclovir or famciclovir.
James R. Stegman, Jill K. Badin, Kaitlyn A. Biles, Thamar Etienne, Sogand Fartash-Naini, Ariel D. Gordon, Zachary W. Greeley, Benjamin W. Harding, Ricardo J. Mack, Danielle Masica, Ashley N. Nelson, Amandeep K. Samra, Sarah E. Smith, Gabrielle P. Thomas, Haley J. Zack, Timothy J. Brunker, Barry J. Margulies, Carla Caramella   +17 more
wiley   +1 more source

HIV‐1 Replication in HIV‐Infected Individuals Is Significantly Reduced When Peripheral Blood Mononuclear Cells Are Superinfected with HSV‐1

The Scientific World Journal, Volume 2012, Issue 1, 2012., 2012
Herpes simplex virus (HSV) can cause generalized infection in human immunodeficiency virus‐ (HIV‐) infected patients leading to death. This study investigated HSV‐1 replication in PBMCs from 25 HIV‐infected individuals and 15 healthy donors and the effects of HSV‐1 superinfection on HIV‐1 production.
Taneth Yamsuwan, Chintana Chirathaworn, Pokrath Hansasuta, Parvapan Bhattarakosol, K. Ikuta, N. Maneekarn, A. Zakhartchouk   +6 more
wiley   +1 more source

Viral Infection in Renal Transplant Recipients

The Scientific World Journal, Volume 2012, Issue 1, 2012., 2012
Viruses are among the most common causes of opportunistic infection after transplantation. The risk for viral infection is a function of the specific virus encountered, the intensity of immune suppression used to prevent graft rejection, and other host factors governing susceptibility.
Jovana Cukuranovic, Sladjana Ugrenovic, Ivan Jovanovic, Milan Visnjic, Vladisav Stefanovic, Stephane Basmaciogullari, Balazs Harrach, Karen Mansfield   +7 more
wiley   +1 more source

Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania. [PDF]

, 2012
OBJECTIVES: Information on pregnancy rates and factors associated with pregnancy and contraceptive use is important for clinical trials in women in sub-Saharan Africa where withdrawal of investigational products may be required in the event of pregnancy ...
Baisley, Kathy, Changalucha, John, Hayes, Richard J, Odutola, Aderonke, Ross, David A, Rusizoka, Mary, Tanton, Clare, Watson-Jones, Deborah, Weiss, Helen A   +8 more
core   +1 more source

Excoecarianin, Isolated from Phyllanthus urinaria Linnea, Inhibits Herpes Simplex Virus Type 2 Infection through Inactivation of Viral Particles

Evidence-Based Complementary and Alternative Medicine, Volume 2011, Issue 1, 2011., 2011
Phyllanthus urinaria Linnea (Euphorbiaceae) is one of the traditional medicinal plants widely used by oriental people to treat various diseases. We have previously demonstrated that the acetone extract of P. urinaria inhibits herpes simplex virus type 2 (HSV‐2) but not HSV‐1 infection.
Hua-Yew Cheng, Chien-Min Yang, Ta-Chen Lin, Liang-Tzung Lin, Lien-Chai Chiang, Chun-Ching Lin   +5 more
wiley   +1 more source

Pathogen burden and cortisol profiles over the day [PDF]

, 2009
Hypothalamic-pituitary-adrenocortical (HPA) regulation in adults is influenced by early psychosocial adversity, but the role of infectious disease history is poorly understood.
Bergstrom, S, Gylfe, A, Henderson, B, Shamaei-Tousi, A, Steptoe, A   +4 more
core   +1 more source