Control of HSV-1 latency in human trigeminal ganglia—current overview [PDF]
, 2018 Although recurrent Herpes simplex virus type 1 (HSV-1) infections are quite common in humans, little is known about the exact molecular mechanisms involved in latency and reactivation of the virus from its stronghold, the trigeminal ganglion.
Derfuss, Tobias, Held, Kathrin
core
Changes in subcellular localization reveal interactions between human cytomegalovirus terminase subunits [PDF]
, 2012 BACKGROUND: During herpesvirus replication, terminase packages viral DNA into capsids. The subunits of herpes simplex virus terminase, UL15, UL28, and UL33, assemble in the cytoplasm prior to nuclear import of the complex.
McVoy, Michael A. +3 more
core +2 more sources
Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania. [PDF]
, 2012 OBJECTIVES: Information on pregnancy rates and factors associated with pregnancy and contraceptive use is important for clinical trials in women in sub-Saharan Africa where withdrawal of investigational products may be required in the event of pregnancy ...
Baisley, Kathy +8 more
core +1 more source
Herpes simplex virus hepatitis 4 years after liver transplantation [PDF]
, 2018 If not promptly recognized and treated, herpes simplex virus (HSV) hepatitis is associated with a high mortality. A patient transplanted for primary sclerosing cholangitis required, 4 years later, a colectomy for a steroid-resistant flare of ulcerative ...
Bernasch, Dirke +4 more
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Enhanced Nigrostriatal Neuron-specific, Long-term Expression by Using Neural-specific Promoters in Combination with Targeted Gene Transfer by Modified Helper Virus-free HSV-1 Vector Particles [PDF]
, 2012 Background: Direct gene transfer into neurons has potential for developing gene therapy treatments for specific neurological conditions, and for elucidating neuronal physiology.
Cao, Haiyan +4 more
core +1 more source
The landscape of viral associations in human cancers [PDF]
, 2020 Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik +14 more
core +3 more sources
Problems of VirologyIntroduction. Herpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family. Smoking is one of the leading causes of disease and premature death worldwide, responsible for the death of up to six million people annually. The purpose of the current study was
Jalil B. Mays +2 more
openaire +1 more source
Cerebrospinal fluid from Alzheimer's disease patients contains fungal proteins and DNA (Review) [PDF]
, 2015 The identification of biomarkers for Alzheimer’s disease is important for patient management and to assess the effectiveness of clinical intervention. Cerebrospinal fluid (CSF) biomarkers constitute a powerful tool for diagnosis and monitoring disease ...
Alonso, Ruth +4 more
core +1 more source
Effect of HSV-2 on population-level trends in HIV incidence in Uganda between 1990 and 2007. [PDF]
, 2013 OBJECTIVE: To assess the long-term effects of population-level HSV-2 infection on HIV incidence. METHODS: Data from a population-based cohort in south-western Uganda were used to estimate HIV incidence from 1990 to 2007.
Biraro, Samuel +6 more
core +1 more source
Pathogen burden and cortisol profiles over the day [PDF]
, 2009 Hypothalamic-pituitary-adrenocortical (HPA) regulation in adults is influenced by early psychosocial adversity, but the role of infectious disease history is poorly understood.
Bergstrom, S +4 more
core +1 more source