Results 71 to 80 of about 8,273 (160)

Measurement and predictors of adherence in a trial of HSV suppressive therapy in Tanzania.

, 2009
This study estimates adherence and identifies predictors of good adherence among 1305 Tanzanian women participating in a randomised, double-blind, placebo-controlled trial of HSV suppressive therapy to reduce HIV incidence or genital HIV shedding.
Baisley, Kathy, Changalucha, John, Clayton, Tim, Hambleton, Ian, Hayes, Richard J, Mugeye, Kokugonza, Ross, David A, Rusizoka, Mary, Tanton, Clare, Watson-Jones, Deborah, Weiss, Helen A   +10 more
core   +1 more source

A full UL13 open reading frame in Marek’s disease virus (MDV) is dispensable for tumor formation and feather follicle tropism and cannot restore horizontal virus transmission of rRB-1B in vivo [PDF]

, 2007
peer reviewedMarek’s disease virus (MDV) is an oncogenic alphaherpesvirus that is highly contagious in poultry. Recombinant RB-1B (rRB-1B) reconstituted from an infectious genome cloned as a bacterial artificial chromosome (BAC) is unable to spread ...
Beaumont, Catherine, Blondeau, Caroline, Chbab, Najet, Courvoisier, Katia, Denesvre, Caroline, Osterrieder, Nikolaus, Vautherot, Jean-Francois   +6 more
core   +4 more sources

Exploring experiences in peer mentoring as a strategy for capacity building in sexual reproductive health and HIV service integration in Kenya. [PDF]

, 2014
BACKGROUND: The Integra Initiative designed, tested, and adapted protocols for peer mentorship in order to improve service providers' skills, knowledge, and capacity to provide quality integrated HIV and sexual and reproductive health (SRH) services ...
Abuya, Timothy, Baird, Averie, Colombini, Manuela, Integra Initiative, Kimani, James Kelly, Kivunaga, Jackline, Mayhew, Susannah, Muia, Ruth Wayua, Mutemwa, Richard, Ndwiga, Charity, Warren, Charlotte E   +10 more
core   +1 more source

Impact of Toll-Like Receptors (TLRs) and TLR Signaling Proteins in Trigeminal Ganglia Impairing Herpes Simplex Virus 1 (HSV-1) Progression to Encephalitis: Insights from Mouse Models

Frontiers in Bioscience-Landmark
Herpes simplex virus 1 (HSV-1) or simplexvirus humanalpha 1 is a neurotropic virus that is responsible for orofacial infections in humans. More than 70% of the world’s population may have seropositivity for HSV-1, and this virus is a leading cause of ...
Marco Antônio Campos, Guilherme de Pádua Zolini, Erna Geessien Kroon   +2 more
doaj   +1 more source

Interferon lambda protects the female reproductive tract against Zika virus infection [PDF]

, 2019
Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood.
Arora, Nitin, Artyomov, Maxim N., Caine, Elizabeth A., Coyne, Carolyn B., Diamond, Michael S., Moley, Kelle H., Scheaffer, Suzanne M., Zaitsev, Konstantin   +7 more
core   +3 more sources

Recurring eczema herpeticum complicated by herpetic meningitis and staphylococcal bacteremia

JEM Reports
Background: Eczema Herpeticum (EH) is a dermatological emergency that may progress to viral meningitis in patients not treated urgently. We present a case of recurrent EH in a young, immunocompetent patient complicated by progressing herpetic meningitis ...
Morgan C. Lain, John R. Bales, Mahmoud D. Al-Fadhl, Anthony V. Thomas, Hamid D. Al-Fadhl, Uzma Rizvi, Joseph B. Miller, Bruce D. Harley, Mark M. Walsh   +8 more
doaj   +1 more source

Can the UNAIDS modes of transmission model be improved? A comparison of the original and revised model projections using data from a setting in west Africa. [PDF]

, 2013
OBJECTIVE: The UNAIDS modes of transmission model (MoT) is a user-friendly model, developed to predict the distribution of new HIV infections among different subgroups. The model has been used in 29 countries to guide interventions. However, there is the
Blanchard, James F, Bobrova, Natalia, Foss, Anna M, Heise, Lori, Momah, Amaka, Ogungbemi, Michael K, Prudden, Holly J, Vickerman, Peter, Watts, Charlotte H   +8 more
core   +1 more source

Control of HSV-1 latency in human trigeminal ganglia—current overview [PDF]

, 2018
Although recurrent Herpes simplex virus type 1 (HSV-1) infections are quite common in humans, little is known about the exact molecular mechanisms involved in latency and reactivation of the virus from its stronghold, the trigeminal ganglion.
Derfuss, Tobias, Held, Kathrin
core  

Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV [PDF]

, 2015
Protein microbicides containing neutralizing antibodies and antiviral lectins may help to reduce the rate of infection with human immunodeficiency virus (HIV) if it is possible to manufacture the components in large quantities at a cost affordable in HIV‐
Arcalis, E, Capell, T, Christou, P, Evans, A, Medina, V, O'Keefe, BR, Ramessar, K, Shattock, RJ, Stöger, E, Vamvaka, E   +9 more
core   +2 more sources

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes [PDF]

, 2017
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the ...
Dreyfus, David H., FAGGIONI, Alberto, FARINA, Antonella, Farina, G. Alessandra, Lacconi, Valentina, Lenna, Stefania, MORRONE, Stefania, PERUZZI, Giovanna, QUARTA, SILVIA, ROSATO, Edoardo, Trojanowska, Maria, VESTRI, Anna Rita, York, Michael   +12 more
core   +1 more source