Technology using simulated microgravity
Regenerative Therapy, 2023 The human body experiences constant stimulation from Earth's gravity, and the absence of gravity leads to various impacts at the cellular and tissue levels.
Yusuke Nishimura
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The mechanosensitive channel ELKIN1 regulates cellular adaptations to simulated microgravity [PDF]
npj MicrogravityIn conditions of microgravity the human body undergoes extensive alterations in physiological function. However, it has proven challenging to determine how these changes are mediated at the molecular and cellular level.
Daphne Wang +5 more
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Impact of simulated microgravity in short-term evolution of an RNA bacteriophage [PDF]
Frontiers in MicrobiologyIntroductionMicrogravity is a critical environmental factor in space that can alter microbial physiology and virus–host interactions. Understanding these effects is essential for planetary protection and crew health during long-term missions ...
Alicia Rodríguez-Moreno +5 more
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Integrated transcriptomic and proteomic analyses identify the TLR2–CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity [PDF]
Frontiers in PhysiologySimulated microgravity profoundly alters endothelial function, particularly cell migration. However, the mechanosensitive molecular pathways involved remain incompletely understood.
Xiaodong Qin +5 more
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The Growth of Soybean (Glycine max) Under Salt Stress Is Modulated in Simulated Microgravity Conditions [PDF]
CellsThe role of a simulated microgravity environment on soybean growth was investigated. The root grew more under simulated microgravity conditions than in the presence of gravity.
Setsuko Komatsu +6 more
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Simulated Microgravity Causes Delayed Platelet Activation and Downregulates Acid-Sensing Ion Channel 1/2 Protein Expression [PDF]
BiomedicinesBackground: Microgravity is a physical force that affects cellular functions, including gene expression, cellular differentiation, proliferation, and signal transduction. Ion channels play an important role in ionic permeability and cell physiology.
Niharika Bala +4 more
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Adaptation to simulated microgravity in Streptococcus mutans
npj Microgravity, 2022 Long-term space missions have shown an increased incidence of oral disease in astronauts’ and as a result, are one of the top conditions predicted to impact future missions.
Mizpha C. Fernander +5 more
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Under simulated microgravity and gravity, anthocyanin is regulated by DcaWRKY2 in Dendrobium catenatum leaves [PDF]
Frontiers in Plant ScienceLong-term space missions will require high-quality plants that are edible, medicinal, and ornamental, to support the physical and mental health of astronauts under altered gravity conditions.
Tianze Hou +5 more
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CeO2 nanomaterial regulates wheat endophytic and rhizospheric bacteria to enhance resistance under simulated microgravity stress [PDF]
npj MicrogravityCertain nanomaterials, including cerium dioxide nanoparticle (CeO2 NP), have shown potential in modulating plant microbial communities to alleviate stressors like simulated microgravity.
Dengbo Chen +7 more
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Effects of simulated microgravity on colorectal cancer organoids growth and drug response [PDF]
Scientific ReportsCellular and molecular dynamics of human cells are constantly affected by gravity. Alteration of the gravitational force disturbs the cellular equilibrium, which might modify physiological and molecular characteristics. Nevertheless, biological responses
Soon-Chan Kim +6 more
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