Results 21 to 30 of about 3,978 (184)
WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity
Frontiers in Cell and Developmental Biology, 2021 Cardiac muscle is extremely sensitive to changes in loading conditions; the microgravity during space flight can cause cardiac remodeling and function decline.
Guohui Zhong +12 more
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Effects of Gravity, Microgravity or Microgravity Simulation on Early Mammalian Development [PDF]
Stem Cells and Development, 2018 Plant and animal life forms evolved mechanisms for sensing and responding to gravity on Earth where homeostatic needs require responses. The lack of gravity, such as in the International Space Station (ISS), causes acute, intra-generational changes in the quality of life.
Douglas M, Ruden +6 more
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Simulated microgravity in the ring-sheared drop [PDF]
npj Microgravity, 2020 AbstractThe ring-sheared drop is a module for the International Space Station to study sheared fluid interfaces and their influence on amyloid fibril formation. A 2.54-cm diameter drop is constrained by a stationary sharp-edged ring at some latitude and sheared by the rotation of another ring in the other hemisphere.
Patrick M. McMackin +7 more
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Simulated Microgravity Using a Rotary Culture System Compromises the In Vitro Development of Mouse Preantral Follicles. [PDF]
PLoS ONE, 2016 Growing cells in simulated weightlessness condition might be a highly promising new technique to maintain or generate tissue constructs in a scaffold-free manner.
Shen Zhang +7 more
doaj +1 more source
Expression pattern of neurotrophins and their receptors during neuronal differentiation of adipose-derived stem cells in simulated microgravity condition [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Studies have confirmed that microgravity, as a mechanical factor, influences both differentiation and function of mesenchymal stem cells. Here we investigated the effects of simulated microgravity on neural differentiation of human adipose ...
Vajiheh Zarrinpour +2 more
doaj +1 more source
Simulated microgravity-induced aortic remodeling
Journal of Applied Physiology, 2009 We have previously shown that microgravity and simulated microgravity induce an increase in human and rat aortic stiffness. We attempted to elucidate the mechanism(s) responsible for this increase in stiffness. We hypothesize that an alteration in vessel wall collagen or elastin content or in extracellular matrix (ECM) cross-linking either individually
Eric C, Tuday +3 more
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Simulated Microgravity Induces Microvolt T Wave Alternans [PDF]
Annals of Noninvasive Electrocardiology, 2005 Background: There are numerous anecdotal reports of ventricular arrhythmias during spaceflight; however, it is not known whether spaceflight or microgravity systematically increases the risk of cardiac dysrhythmias. Microvolt T wave alternans (MTWA) testing compares favorably with other noninvasive risk stratifiers and invasive electrophysiological ...
S Marlene, Grenon +7 more
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Studies in microgravity, simulated microgravity and gravity do not support a gravitostat [PDF]
Journal of Endocrinology, 2020 The gravitostat is purported to function as a leptin-independent, osteocyte-dependent mechanism for regulation of energy balance. If correct, reduced activation of gravitostat signaling caused by prolonged sitting may contribute to obesity. The gravitostat concept is supported by reduced body mass in rodents following surgical implantation of weighted ...
Russell T, Turner +4 more
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Cellular Physiology and Biochemistry, 2017 Background/aims: Microgravity leads to hydrodynamic alterations in the cardiovascular system and is associated with increased angiogenesis, an important aspect of endothelial cell behavior to initiate new vessel growth.
Fei Shi +13 more
doaj +1 more source
Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem Cells
Cellular Physiology and Biochemistry, 2016 Background/Aims: Embryonic developmental studies under microgravity conditions in space are very limited. To study the effects of altered gravity on the embryonic development processes we established an in vitro methodology allowing differentiation of ...
Vaibhav Shinde +11 more
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