Results 51 to 60 of about 586,504 (304)

Delayed acceptance ABC-SMC [PDF]

, 2020
Approximate Bayesian computation (ABC) is now an established technique for statistical inference used in cases where the likelihood function is computationally expensive or not available. It relies on the use of a~model that is specified in the form of a~
Everitt, Richard G., Rowińska, Paulina A.   +1 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Improving Coral Grow-Out Through an Integrated Aquaculture Approach

Aquaculture Nutrition
Some coral species in natural reef systems derive benefits from fish which live in close association with them. This study investigates the benefits of incorporating fish in ex situ coral culture to enhance coral physiological performance.
Rachel C. Neil, Jonathan A. Barton, Andrew Heyward, David S. Francis, Leo Nankervis, Thomas S. Mock, David G. Bourne, Craig Humphrey   +7 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Facial Expression Simulator Control System using OpenGL Graphical Simulator [PDF]

, 2010
Verbal communication is communication that uses the language or voice interaction, whereas nonverbal communication is communication that interacts with one of these gestures is to show facial expressions.
Sulistijono, Indra Aji
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Design of cooling system in space solar array simulator

Dianzi Jishu Yingyong, 2019
For the high power solar array simulator, the requirements such as high power, miniaturization and modularization are higher. In this paper the total power of the simulator is 2.4 kW with the chassis height is no more than 2U.
Zhang Jian, Wang Zicai, Zhang Hua, Zhang Donglai   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance

Communications Biology
Corals at very early life stages face high mortality bottlenecks, limiting natural stock-recruitment and the success of restoration and aquaculture strategies reliant on sexual reproduction.
Jennifer L. Matthews, Natasha Bartels, Hannah Kish, Laura La Motta, Matthew P. Padula, David J. Hughes, Zoe J. Crane, Craig Humphrey, Nadine Boulotte, Christine Roper, Madeleine J. H. van Oppen, Jean-Baptiste Raina, David J. Suggett   +12 more
doaj   +1 more source