Rapid Field Immunoassay for Detecting Antibody to Sin Nombre Virus in Deer Mice [PDF]
We developed a 1-hour field enzyme immunoassay (EIA) for detecting antibody to Sin Nombre virus in deer mice (Peromyscus maniculatus). The assay specificity and sensitivity were comparable to those of a standard EIA.
Tony Schountz +6 more
doaj +4 more sources
Sin Nombre Virus Infection in Deer Mice, Channel Islands, California [PDF]
To the Editor: Sin Nombre virus (SNV) is a highly virulent strain of hantavirus associated with rodent hosts in North America (1,2). Documenting the prevalence of SNV in wild rodent populations is an important component of determining risk for exposure and ultimately providing sound recommendations for epidemiologic management (3). Prevalence of SNV is
John L. Orrock, Brian F. Allan
doaj +4 more sources
Natural History of Sin Nombre Virus in Western Colorado
A mark-recapture longitudinal study of immunoglobulin G (IgG) antibody to Sin Nombre virus (SNV) in rodent populations in western Colorado (1994—results summarized to October 1997) indicates the presence of SNV or a closely related hantavirus at two ...
Charles H. Calisher +3 more
doaj +3 more sources
Elevated Cytokines, Thrombin and PAI-1 in Severe HCPS Patients Due to Sin Nombre Virus [PDF]
Sin Nombre Hantavirus (SNV, Bunyaviridae Hantavirus) is a Category A pathogen that causes Hantavirus Cardiopulmonary Syndrome (HCPS) with case fatality ratios generally ranging from 30% to 50%.
Virginie Bondu +6 more
doaj +2 more sources
Novel Focus of Sin Nombre Virus in Peromyscus eremicus Mice, Death Valley National Park, California, USA [PDF]
The deer mouse (Peromyscus maniculatus) is the primary reservoir for Sin Nombre virus (SNV) in the western United States. Rodent surveillance for hantavirus in Death Valley National Park, California, USA, revealed cactus mice (P.
Joseph E. Burns +8 more
doaj +2 more sources
Sin Nombre Virus in Deer Mice Captured Inside Homes, Southwestern Montana [PDF]
From 1996 through 1999, 35 deer mice (Peromyscus maniculatus) were captured in 25 urban and suburban homes in southwestern Montana. Mice were captured throughout the year except for January; seven mice (20%) from seven (28%) of the homes were ...
Amy J. Kuenzi +2 more
doaj +3 more sources
A Longitudinal Study of Sin Nombre Virus Prevalence in Rodents, Southeastern Arizona
We determined the prevalence of Sin Nombre virus antibodies in small mammals in southeastern Arizona. Of 1,234 rodents (from 13 species) captured each month from May through December 1995, only mice in the genus Peromyscus were seropositive.
Amy J. Kuenzi +4 more
doaj +3 more sources
Sin nombre virus and rodent species diversity: a test of the dilution and amplification hypotheses. [PDF]
BACKGROUND:Species diversity is proposed to greatly impact the prevalence of pathogens. Two predominant hypotheses, the "Dilution Effect" and the "Amplification Effect", predict divergent outcomes with respect to the impact of species diversity.
Christine A Clay +3 more
doaj +2 more sources
Structural and functional characterization of the Sin Nombre virus L protein. [PDF]
The Bunyavirales order is a large and diverse group of segmented negative-strand RNA viruses. Several virus families within this order contain important human pathogens, including Sin Nombre virus (SNV) of the Hantaviridae. Despite the high epidemic potential of bunyaviruses, specific medical countermeasures such as vaccines or antivirals are missing ...
Meier K +10 more
europepmc +7 more sources
Patients who later have a mild course of hantavirus cardiopulmonary syndrome (HCPS) are more likely to exhibit a high titer of neutralizing antibodies against Sin Nombre virus (SNV), the etiologic agent of HCPS, at the time of hospital admission. Because
Chunyan Ye +4 more
doaj +3 more sources

