Results 51 to 60 of about 22,694 (182)

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

mBio, 2020
Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer   +10 more
doaj   +1 more source

Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

Cell Reports, 2021
Summary: New World hantaviruses (NWHs) are endemic in North and South America and cause hantavirus cardiopulmonary syndrome (HCPS), with a case fatality rate of up to 40%. Knowledge of the natural humoral immune response to NWH infection is limited. Here,
Taylor B. Engdahl, Natalia A. Kuzmina, Adam J. Ronk, Chad E. Mire, Matthew A. Hyde, Nurgun Kose, Matthew D. Josleyn, Rachel E. Sutton, Apoorva Mehta, Rachael M. Wolters, Nicole M. Lloyd, Francisca R. Valdivieso, Thomas G. Ksiazek, Jay W. Hooper, Alexander Bukreyev, James E. Crowe, Jr.   +15 more
doaj   +1 more source

Antibody to sin nombre virus in rodents associated with peridomestic habitats in west central Montana. [PDF]

American Journal of Tropical Medicine and Hygiene, 2001
A. Kuenzi, R. Douglass, D. White, C. Bond, J. Mills   +4 more
semanticscholar   +2 more sources

A novel Sin Nombre virus DNA vaccine and its inclusion in a candidate pan-hantavirus vaccine against hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). [PDF]

Vaccine, 2013
Hooper JW, Josleyn M, Ballantyne J, Brocato R.   +3 more
europepmc   +2 more sources

Hantavirus and Arenavirus Antibodies in Persons with Occupational Rodent Exposure, North America

Emerging Infectious Diseases, 2007
Rodents are the principal hosts of Sin Nombre virus, 4 other hantaviruses known to cause hantavirus pulmonary syndrome in North America, and the 3 North American arenaviruses.
Charles F. Fulhorst, Mary Louise Milazzo, Lori R. Armstrong, James E. Childs, Pierre E. Rollin, Rima Khabbaz, C.J. Peters, Thomas G. Ksiazek   +7 more
doaj   +1 more source

Sin nombre virus glycoprotein trafficking

Virology, 2003
Sin Nombre virus (SNV) is a major representative of the New World hantaviruses and the most common cause of hantavirus pulmonary syndrome (HPS) with high mortality in North America. Unlike other members of the family Bunyaviridae which mature in the Golgi complex, New World hantaviruses have been previously reported to mature at the cell surface.
Spiropoulou, C.F, Goldsmith, C.S, Shoemaker, T.R, Peters, C.J, Compans, R.W   +4 more
openaire   +2 more sources

Biodefense Implications of New-World Hantaviruses

Frontiers in Bioengineering and Biotechnology, 2020
Hantaviruses, part of the Bunyaviridae family, are a genus of negative-sense, single-stranded RNA viruses that cause two major diseases: New-World Hantavirus Cardiopulmonary Syndrome and Old-World Hemorrhagic Fever with Renal Syndrome.
Michael Hilary D’Souza, Trushar R. Patel, Trushar R. Patel, Trushar R. Patel   +3 more
doaj   +1 more source

Sin Nombre Virus mRNA Synthesis

Virology, 1996
Sin Nombre (SN) virus is the major etiologic agent of hantavirus pulmonary syndrome, a severe respiratory disease with high mortality. Like other hantaviruses, SN virus causes an inapparent chronic infection of the natural rodent reservoir and tends to grow slowly and produce little cytopathic effect even in highly susceptible Vero E6 tissue culture ...
Hutchinson, Karen L., Peters, Clarence J., Nichol, Stuart T.   +2 more
openaire   +2 more sources

Naturally Occurring Sin Nombre Virus Genetic Reassortants

Virology, 1995
Genetic reassortment has been shown to play an important role in the evolution of several segmented RNA viruses and in the epidemiology of associated diseases. Sin Nombre (SN) virus is the cause of hantavirus pulmonary syndrome throughout the western United States.
HENDERSON, WINNIE W., MONROE, MARTHA C., ST. JEOR, STEPHEN C., THAYER, WESLEY P., ROWE, JOAN E., PETERS, C.J., NICHOL, STUART T.   +6 more
openaire   +2 more sources

Removing Deer Mice from Buildings and the Risk for Human Exposure to Sin Nombre Virus

Emerging Infectious Diseases, 2003
Trapping and removing deer mice from ranch buildings resulted in an increased number of mice, including Sin Nombre virus antibody–positive mice, entering ranch buildings.
Richard J. Douglass, Amy J. Kuenzi, Courtney Y. Williams, Samuel J. Douglass, James N. Mills   +4 more
doaj   +1 more source