Results 111 to 120 of about 1,693,733 (308)
Single‐cell genomics meets systems neuroscience: Insights from mapping the brain circuitry of stress
Abstract Responses to external and internal dangers is essential for survival and homeostatic regulation. Hypothalamic corticotropin‐releasing hormone neurons (CRHNs) play a pivotal role in regulating neuroendocrine responses to fear and stress.
Naresh K. Hanchate
wiley +1 more source
Summary We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm.
Dawson Alistair +2 more
doaj +1 more source
Cell culture-adapted strains of Sindbis virus (SINV) initially attach to cells by the ability to interact with heparan sulfate (HS) through selective mutation for positively charged amino acid (aa) scattered in E2 glycoprotein (W. B. Klimstra, K.
Wu-Yang Zhu +8 more
semanticscholar +1 more source
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. [PDF]
The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections.
Bozzacco, Leonia +8 more
core
Genetically‐targeted control of the spinal cord and peripheral nervous system
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano +3 more
wiley +1 more source
Establishment of a New Real-Time Molecular Assay for the Detection of Babanki Virus in Africa
Babanki virus is a subtype of the Sindbis virus, a widespread arthropod-borne alphavirus circulating in Eurasia, Africa, and Oceania. Characterized by rashes and arthritis, clinical infections due to Sindbis were mainly reported in Africa, Australia ...
Martin Faye +10 more
doaj +1 more source
The alphaviruses: gene expression, replication, and evolution [PDF]
The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for these viruses.
Strauss, Ellen G., Strauss, James H.
core +1 more source
Density waves theory of the capsid structure of small icosahedral viruses
We apply Landau theory of crystallization to explain and to classify the capsid structures of small viruses with spherical topology and icosahedral symmetry.
D. L. D. Caspar +8 more
core +3 more sources
Activity-dependent dynamics and sequestration of proteasomes in dendritic spines [PDF]
The regulated degradation of proteins by the ubiquitin proteasome pathway is emerging as an important modulator of synaptic function and plasticity. The proteasome is a large, multi-subunit cellular machine that recognizes, unfolds and degrades target ...
Bingol, Baris, Schuman, Erin M.
core +1 more source
Class of {varphi}X174 Mutants Relatively Deficient in Synthesis of Viral RNA [PDF]
Nonpermissive cells infected with {varphi}X174 gene D amber mutants synthesized some sixfold less viral RNA than permissive cells. The decrease was unaffected by increasing the multiplicity of infection and was a consequence of an overall decrease in all
Clements, J. Barklie +1 more
core

