Genetic determinants of Sindbis virus neuroinvasiveness [PDF]
After peripheral inoculation of mice, Sindbis virus replicates in a variety of tissues, leading to viremia. In some cases, the virus can enter the central nervous system (CNS) and cause lethal encephalitis. The outcome of infection is age and virus strain dependent.
Jean Dubuisson +4 more
openalex +4 more sources
Sindbis Virus with a Tricomponent Genome [PDF]
ABSTRACT We established a system for propagation of Sindbis virus (SIN)-based replicons in tissue culture in the form of a tricomponent genome virus. Three RNA fragments containing complementing genetic information required for virus replication are packaged into separate viral particles, and each cell produces at least 1,000 packaged ...
Rafik Fayzulin +4 more
openalex +3 more sources
Vertical Transmission of Sindbis Virus in Culex Mosquitoes [PDF]
Vertical transmission (VT) is a phenomenon of vector-borne diseases where a pathogen is transferred from an infected arthropod mother to her offspring.
Emma Dahl +4 more
doaj +2 more sources
Genomic Analysis of Sindbis Virus Reveals Uncharacterized Diversity within the Australasian Region, and Support for Revised SINV Taxonomy [PDF]
Sindbis virus (SINV) is a widely dispersed mosquito-borne alphavirus. Reports of Sindbis disease are largely restricted to northern Europe and South Africa.
Alice Michie +6 more
doaj +2 more sources
Sindbis virus neutralising antibodies detected in Swedish horses [PDF]
A number of viruses transmitted by mosquitoes are well known to cause disease in both humans and horses, ranging from mild fevers to mortal neurological disease.
Agnes Björnström +3 more
doaj +2 more sources
Sindbis virus is suppressed in the yellow fever mosquito <i>Aedes aegypti</i> by Atg6/BECN1 (autophagy-related 6)-mediated activation of autophagy. [PDF]
Pujhari S +5 more
europepmc +3 more sources
Sindbis Virus Vaccine Platform: A Promising Oncolytic Virus-Mediated Approach for Ovarian Cancer Treatment. [PDF]
Pampeno C, Opp S, Hurtado A, Meruelo D.
europepmc +3 more sources
32 P-labeled ribonucleic acid (RNA) from purified Sindbis virus was examined for the presence of hidden breaks. Viral RNA was treated with acid at p H 2.9 or with formaldehyde and was analyzed on sucrose gradients or by polyacrylamide gel electrophoresis.
B M, Arif, P, Faulkner
openaire +2 more sources
Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes. [PDF]
Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein.
J Jordan Steel +4 more
doaj +1 more source
Corrigendum to " First isolation of the Sindbis virus in mosquitoes from southwestern Spain reveals a new recent introduction from Africa [One Health, Volume 20, 100947]". [PDF]
Gutiérrez-López R +14 more
europepmc +2 more sources

