Nanopipettes as Monitoring Probes for the Single Living Cell: State of the Art and Future Directions in Molecular Biology. [PDF]
, 2018 Examining the behavior of a single cell within its natural environment is valuable for understanding both the biological processes that control the function of cells and how injury or disease lead to pathological change of their function.
Bulbul, Gonca +4 more
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Automated single-cell motility analysis on a chip using lensfree microscopy. [PDF]
, 2014 Quantitative cell motility studies are necessary for understanding biophysical processes, developing models for cell locomotion and for drug discovery.
Di Carlo, Dino +6 more
core +1 more source
ChemInform Abstract: Single Cell Analysis at the Nanoscale
ChemInform, 2012 AbstractReview: 73 refs.
Xin Ting Zheng +2 more
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STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]
, 2017 The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne +5 more
core +2 more sources
Deep generative modeling for single-cell transcriptomics. [PDF]
, 2018 Single-cell transcriptome measurements can reveal unexplored biological diversity, but they suffer from technical noise and bias that must be modeled to account for the resulting uncertainty in downstream analyses.
A Regev +39 more
core +1 more source
SCALA: A complete solution for multimodal analysis of single-cell Next Generation Sequencing data
Computational and Structural Biotechnology Journal, 2023 Analysis and interpretation of high-throughput transcriptional and chromatin accessibility data at single-cell (sc) resolution are still open challenges in the biomedical field.
Christos Tzaferis +5 more
doaj +1 more source
Laser-fabricated cell patterning stencil for single cell analysis
BMC Biotechnology, 2017 Precise spatial positioning and isolation of mammalian cells is a critical component of many single cell experimental methods and biological engineering applications.
Jacob J. Messner +2 more
doaj +1 more source
A microfluidic processor for gene expression profiling of single human embryonic stem cells [PDF]
, 2008 The gene expression of human embryonic stem cells (hESC) is a critical aspect for understanding the normal and pathological development of human cells and tissues.
Chen, Yan +6 more
core +1 more source
Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy. [PDF]
, 2018 The rapid screening and isolation of single leukemia cells from blood has become critical for early leukemia detection and tumor heterogeneity interrogation. However, due to the size overlap between leukemia cells and the more abundant white blood cells (
Digman, Michelle A +4 more
core +1 more source
Single-Cell Genomic Analysis in Plants [PDF]
Genes, 2018 Individual cells in an organism are variable, which strongly impacts cellular processes. Advances in sequencing technologies have enabled single-cell genomic analysis to become widespread, addressing shortcomings of analyses conducted on populations of bulk cells. While the field of single-cell plant genomics is in its infancy, there is great potential
Yuxuan Yuan +4 more
openaire +4 more sources