Results 41 to 50 of about 4,724,822 (306)

Development of Droplet Microfluidics Enabling High-Throughput Single-Cell Analysis

Molecules, 2016
This article reviews recent developments in droplet microfluidics enabling high-throughput single-cell analysis. Five key aspects in this field are included in this review: (1) prototype demonstration of single-cell encapsulation in microfluidic droplets;
Na Wen, Zhan Zhao, Beiyuan Fan, Deyong Chen, Dong Men, Junbo Wang, Jian Chen   +6 more
doaj   +1 more source

Single Cell Analysis in Vascular Biology

Frontiers in Cardiovascular Medicine, 2020
The ability to quantify DNA, RNA, and protein variations at the single cell level has revolutionized our understanding of cellular heterogeneity within tissues.
Nicholas W. Chavkin, Karen K. Hirschi, Karen K. Hirschi   +2 more
doaj   +1 more source

Analysis of the paired TCR α- and β-chains of single human T cells. [PDF]

, 2012
Analysis of the paired i.e. matching TCR α- and β-chain rearrangements of single human T cells is required for a precise investigation of clonal diversity, tissue distribution and specificity of protective and pathologic T-cell mediated immune responses.
Dornmair, K., Besgen, P., Held, K., Bhonsle, L., Vollmer, Sigrid, Song-Min Kim, Jens Nickel, Anna Backes, Held, Kathrin, Vollmer, S., Joerg C Prinz, Backes Anna, Backes, A., Backes, Anna, Bhonsle, Latika, Kim Song-Min, Nickel, Jens, Sigrid Vollmer, Nickel, J., Kim, Song-Min, Klaus Dornmair, Dornmair, Klaus, Kim, S., Besgen Petra, Petra Besgen, Vollmer Sigrid, Prinz, Joerg C., Prinz Joerg C., Latika Bhonsle, Bhonsle Latika, Besgen, Petra, Held Kathrin, Prinz, J., Kathrin Held, Nickel Jens, Dornmair Klaus   +35 more
core   +1 more source

Laser-fabricated cell patterning stencil for single cell analysis

BMC Biotechnology, 2017
Precise spatial positioning and isolation of mammalian cells is a critical component of many single cell experimental methods and biological engineering applications.
Jacob J. Messner, Honor L. Glenn, Deirdre R. Meldrum   +2 more
doaj   +1 more source

Artificial intelligence‐assisted automatic and index‐based microbial single‐cell sorting system for One‐Cell‐One‐Tube

mLife, 2022
Identification, sorting, and sequencing of individual cells directly from in situ samples have great potential for in‐depth analysis of the structure and function of microbiomes.
Zhidian Diao, Lingyan Kan, Yilong Zhao, Huaibo Yang, Jingyun Song, Chen Wang, Yang Liu, Fengli Zhang, Teng Xu, Rongze Chen, Yuetong Ji, Xixian Wang, Xiaoyan Jing, Jian Xu, Yuandong Li, Bo Ma   +15 more
doaj   +1 more source

Micro/Nanofluidic Devices for Single Cell Analysis

Micromachines, 2014
The Special Issue of Micromachines entitled “Micro/Nanofluidic Devices for Single Cell Analysis” covers recent advancements regarding the analysis of single cells by different microfluidic approaches.
Tuhin Subhra Santra, Fan Gang Tseng
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

The prospects of single‐cell analysis in autoimmunity [PDF]

Scandinavian Journal of Immunology, 2020
AbstractIn the last decade, there has been a tremendous development of technologies focused on analysing various molecular attributes in single cells, with an ever‐increasing number of parameters becoming available at the DNA, RNA and protein levels. Much of this progress has involved cells in suspension, but also in situ analysis of tissues has taken ...
André Sulen, Shahinul Islam, Anette S. B. Wolff, Bergithe E. Oftedal   +3 more
openaire   +2 more sources

ScRNAPip: A systematic and dynamic pipeline for single‐cell RNA sequencing analysis

iMeta, 2023
With the advancement of sequencing technology, cell separation, and whole‐genome amplification techniques, single cell technology for genome sequencing is emerging gradually.
Limin Xu, Jing Zhang, Yiqian He, Qianqian Yang, Tianhao Mu, Qiushi Guo, Yingqiang Li, Tian Tong, Shifu Chen, Richard D. Ye   +9 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source