Results 31 to 40 of about 4,724,822 (306)
IGDB-DuLab/Single-cell-phenotype-analysis: SCAP
, 2022 This repository contains the source code used in our study titled "Defect-Buffering Cellular Plasticity Increases Robustness of Metazoan Embryogenesis". The provided scripts allow quantification and phenotypic determination of six types of developmental ...
IGDB-DuLab
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Transcriptome Analysis of Single Cells [PDF]
Journal of Visualized Experiments, 2011 Many gene expression analysis techniques rely on material isolated from heterogeneous populations of cells from tissue homogenates or cells in culture. In the case of the brain, regions such as the hippocampus contain a complex arrangement of different cell types, each with distinct mRNA profiles.
Morris, Jacqueline +2 more
openaire +2 more sources
Hierarchical mechanism of amino acid sensing by the T-box riboswitch
Nature Communications, 2018 Riboswitches on 5′ ends of mRNAs are important for bacterial gene regulation. Here the authors probe the mechanism of a tRNA aminoacylation sensing T-box riboswitch using single-molecule fluorescence microscopy to characterize dynamic solution ...
Krishna C. Suddala +5 more
doaj +1 more source
Microfluidics-Based Single-Cell Research for Intercellular Interaction
Frontiers in Cell and Developmental Biology, 2021 Intercellular interaction between cell–cell and cell–ECM is critical to numerous biology and medical studies, such as stem cell differentiation, immunotherapy and tissue engineering. Traditional methods employed for delving into intercellular interaction
Long Pang +10 more
doaj +1 more source
Single Cell Mass Spectrometry Metabolomics Study of Drug-resistant Cells [PDF]
, 2022 Single cell analysis is an emerging area to reveal the heterogeneity of individual cells among all populations. Understanding the cell-to-cell variation can greatly promote the development of drug discovery, disease diagnostics and prognostics ...
Chen, Xingxiu
core
Microfluidic Single-Cell Manipulation and Analysis: Methods and Applications
Micromachines, 2019 In a forest of a hundred thousand trees, no two leaves are alike. Similarly, no two cells in a genetically identical group are the same. This heterogeneity at the single-cell level has been recognized to be vital for the correct interpretation of ...
Tao Luo, Lei Fan, Rong Zhu, Dong Sun
doaj +1 more source
scDA: Single cell discriminant analysis for single-cell RNA sequencing data
Computational and Structural Biotechnology Journal, 2021 Single-cell RNA-sequencing (scRNA-seq) techniques provide unprecedented opportunities to investigate phenotypic and molecular heterogeneity in complex biological systems.
Qianqian Shi +4 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2004 Resistance and susceptibility in barley to the powdery mildew fungus (Blumeria graminis f. sp. hordei) is determined at the single-cell level. Even in genetically compatible interactions, attacked plant epidermal cells defend themselves against attempted
Torben Gjetting +3 more
doaj +1 more source
SCALA: A complete solution for multimodal analysis of single-cell Next Generation Sequencing data
Computational and Structural Biotechnology Journal, 2023 Analysis and interpretation of high-throughput transcriptional and chromatin accessibility data at single-cell (sc) resolution are still open challenges in the biomedical field.
Christos Tzaferis +5 more
doaj +1 more source
Single Cell Proteomics Analysis of Drug Response Shows its Potential as a Drug Discovery Platform
, 2022 Single-cell analysis has clearly established itself in biology and biomedical fields as an invaluable tool that allows one to comprehensively understand the relationship between cells, including their types, states, transitions, trajectories, and spatial
Zachary, Niziolek +3 more
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