Results 31 to 40 of about 5,699,590 (286)

STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]

open access: yes, 2017
The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne   +5 more
core   +2 more sources

Laser-fabricated cell patterning stencil for single cell analysis

open access: yesBMC Biotechnology, 2017
Precise spatial positioning and isolation of mammalian cells is a critical component of many single cell experimental methods and biological engineering applications.
Jacob J. Messner   +2 more
doaj   +1 more source

Deep generative modeling for single-cell transcriptomics. [PDF]

open access: yes, 2018
Single-cell transcriptome measurements can reveal unexplored biological diversity, but they suffer from technical noise and bias that must be modeled to account for the resulting uncertainty in downstream analyses.
A Regev   +39 more
core   +1 more source

A microfluidic processor for gene expression profiling of single human embryonic stem cells [PDF]

open access: yes, 2008
The gene expression of human embryonic stem cells (hESC) is a critical aspect for understanding the normal and pathological development of human cells and tissues.
Chen, Yan   +6 more
core   +1 more source

Transcriptome Analysis of Single Cells [PDF]

open access: yesJournal of Visualized Experiments, 2011
Many gene expression analysis techniques rely on material isolated from heterogeneous populations of cells from tissue homogenates or cells in culture. In the case of the brain, regions such as the hippocampus contain a complex arrangement of different cell types, each with distinct mRNA profiles.
Morris, Jacqueline   +2 more
openaire   +2 more sources

Artificial intelligence‐assisted automatic and index‐based microbial single‐cell sorting system for One‐Cell‐One‐Tube

open access: yesmLife, 2022
Identification, sorting, and sequencing of individual cells directly from in situ samples have great potential for in‐depth analysis of the structure and function of microbiomes.
Zhidian Diao   +15 more
doaj   +1 more source

Poly(ADP-ribose)polymerase activity controls plant growth by promoting leaf cell number [PDF]

open access: yes, 2014
A changing global environment, rising population and increasing demand for biofuels are challenging agriculture and creating a need for technologies to increase biomass production.
Claeys, Hannes   +8 more
core   +3 more sources

Micro/Nanofluidic Devices for Single Cell Analysis

open access: yesMicromachines, 2014
The Special Issue of Micromachines entitled “Micro/Nanofluidic Devices for Single Cell Analysis” covers recent advancements regarding the analysis of single cells by different microfluidic approaches.
Tuhin Subhra Santra, Fan Gang Tseng
doaj   +1 more source

Stochastic modeling for the COMET-assay [PDF]

open access: yes, 2003
We present a stochastic model for single cell gel electrophoresis (COMET-assay) data. Essential is the use of point process structures, renewal theory and reduction to intensity histograms for further data ...
Boulesteix, Anne-Laure   +2 more
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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