The role of hemoglobin in nitric oxide transport in vascular system
Medicine in Novel Technology and Devices, 2020 Nitric oxide (NO) plays a pivotal role in vascular homeostasis and its functions practice in a dose-dependent manner in which too high and too low NO concentration may both induce the development of cardiovascular diseases, which indicates the balance ...
Haoran Su +4 more
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Electrical Characterization and Analysis of Single Cells and Related Applications
Biosensors, 2023 Biological parameters extracted from electrical signals from various body parts have been used for many years to analyze the human body and its behavior.
Weitao Zhu +6 more
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Single‐cell proteomic analysis
WIREs Mechanisms of Disease, 2020 AbstractThe ability to comprehensively profile proteins in every individual cell of complex biological systems is crucial to advance our understanding of normal physiology and disease pathogenesis. Conventional bulk cell experiments mask the cell heterogeneity in the population, while the single‐cell imaging methods suffer from the limited multiplexing
Thai Pham +3 more
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Trajectory-based differential expression analysis for single-cell sequencing data [PDF]
, 2020 Trajectory inference has radically enhanced single-cell RNA-seq research by enabling the study of dynamic changes in gene expression. Downstream of trajectory inference, it is vital to discover genes that are (i) associated with the lineages in the ...
Cannoodt, Robrecht +7 more
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Microfluidic single‐cell multiomics analysis
View, 2023 Cellular heterogeneity is essential to biological processes, such as embryonic development, cell differentiation, and the progression of disease. Recent years have seen the development of a variety of single‐cell multiomics technologies that systemically
Xing Xu +8 more
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Single cell measurement of telomerase expression and splicing using microfluidic emulsion cultures. [PDF]
, 2014 Telomerase is a reverse transcriptase that maintains telomeres on the ends of chromosomes, allowing rapidly dividing cells to proliferate while avoiding senescence and apoptosis.
Hart, Kristina +2 more
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Microfluidic Compartmentalization Platforms for Single Cell Analysis
Biosensors, 2022 Many cellular analytical technologies measure only the average response from a cell population with an assumption that a clonal population is homogenous.
Xuhao Luo +3 more
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An end-to-end software solution for the analysis of high-throughput single-cell migration data [PDF]
, 2017 The systematic study of single-cell migration requires the availability of software for assisting data inspection, quality control and analysis. This is especially important for high-throughput experiments, where multiple biological conditions are tested
Ampe, Christophe +5 more
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Label-Free Metabolic Classification of Single Cells in Droplets Using the Phasor Approach to Fluorescence Lifetime Imaging Microscopy. [PDF]
, 2019 Characterization of single cell metabolism is imperative for understanding subcellular functional and biochemical changes associated with healthy tissue development and the progression of numerous diseases.
Aghaamoo, Mohammad +4 more
core +1 more source
EpiScanpy: integrated single-cell epigenomic analysis [PDF]
Nature Communications, 2021 Abstract EpiScanpy is a toolkit for the analysis of single-cell epigenomic data, namely single-cell DNA methylation and single-cell ATAC-seq data. To address the modality specific challenges from epigenomics data, epiScanpy quantifies the epigenome using multiple feature space constructions and builds a nearest neighbour graph using ...
Anna Danese +5 more
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