Results 231 to 240 of about 2,352,277 (290)

Dual-omics analysis of key biomarkers in T cell ubiquitination of rheumatoid arthritis blood and synovial tissue, validated by two-sample Mendelian randomization and qPCR. [PDF]

Front Immunol
He D, Zhao H, Meng J.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Single cell analysis tools for gene expression by Salmonella Typhimurium

, 2016
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Annotation-free prediction of immunotherapy response in melanoma using single-cell transcriptomic data. [PDF]

PLoS One
Oh DE, Kee G, Oh JH, Kim W, Kang YG, Park CW, Jun TJ, Sung CO.   +7 more
europepmc   +1 more source

Single-cell transcriptomic profiling combined with Mendelian randomization illuminates molecular drivers of bladder cancer. [PDF]

Mol Genet Genomics
He J, Jiang Z, Peng S, Peng L, Xia Z, Ma T, Tan X, Long Q, Wu J.   +8 more
europepmc   +1 more source

Cross-tissue integrative transcriptomic and multimodal analyses suggest shared immune signatures linking lupus nephritis and cutaneous lupus erythematosus. [PDF]

Front Immunol
Li M, Song C, Wang Z, Yuan H, Zhang Z, Sun Y, Zhang F, Wang S, Sun H, Zhao H, Zhu L, Wang D, Li Y.   +12 more
europepmc   +1 more source

Single-cell analysis of a salmonid immune system (river brown trout Salmo trutta fario) reveals evolutionary divergence and hatchery-induced transcriptional reprogramming. [PDF]

BMC Biol
Ord J, Martinez HS, Solbakken MH, Berezenko A, Oberhaensli S, Talker S, Schmidt-Posthaus H, Adrian-Kalchhauser I.   +7 more
europepmc   +1 more source

Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex. [PDF]

Nat Commun
Ruf WP, Kühlwein JK, Meier L, Brockmann SJ, LeeBae J, Sadri-Vakili G, Yilmazer-Hanke D, Petri S, Thal DR, Grozdanov V, Danzer KM.   +10 more
europepmc   +1 more source