Results 21 to 30 of about 1,731,641 (260)

Role of cyclic AMP in the control of cell-specific gene expression [PDF]

, 1993
Genes have to be expressed in specific cell types at appropriate times of development dependent on external signals. cAMP signaling occurs in all cells, thus raising the question of how this signal transduction pattern is integrated into mechanisms ...
Boshart, Michael, Schmid, Wolfgang, Schütz, Günther, Nitsch, Doris   +3 more
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A hierarchical model of transcriptional dynamics allows robust estimation of transcription rates in populations of single cells with variable gene copy number [PDF]

, 2013
Motivation: cis-regulatory DNA sequence elements, such as enhancers and silencers, function to control the spatial and temporal expression of their target genes.
Woodcock, Dan J, Woodcock, Dan J., Koentges, Georgy, Vance, Keith W, Komorowski, Michal, Rand, D. A. (David A.), Vance, Keith W., Finkenstädt, Bärbel, Rand, David A   +8 more
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TLM-Quant : an open-source pipeline for visualization and quantification of gene expression heterogeneity in growing microbial cells [PDF]

, 2013
Gene expression heterogeneity is a key driver for microbial adaptation to fluctuating environmental conditions, cell differentiation and the evolution of species. This phenomenon has therefore enormous implications, not only for life in general, but also
Piersma, Sjouke, Sjouke Piersma (434244), Rudi H J Tonk, Emma L. Denham (121430), Jan Maarten van Dijl, Tonk Rudi H. J., Jan Maarten van Dijl (90770), Samuel Drulhe, Schwikowski Benno, Denham, Emma, Schwikowski, Benno, Piersma Sjouke, Drulhe, Samuel, Drulhe Samuel, Denham, Emma L., van Dijl, Jan Maarten, van Dijl Jan Maarten, Sjouke Piersma, Dijl, Jan Maarten van, Benno Schwikowski (434247), Tonk, Rudi H. J., Rudi H. J. Tonk (434246), Samuel Drulhe (434245), Benno Schwikowski, Emma L Denham, Denham Emma L.   +25 more
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Consensus clustering and functional interpretation of gene-expression data [PDF]

, 2004
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters.
Liu, X, Orengo, Christine, Martin, N, Kellam, P., Paul Kellam, Liu, X., Swift, Stephen, Swift, S, Orengo, C.A., Tucker, Allan, Tucker, A., Tucker, A, Liu, XH, Allan Tucker, Vinciotti, Veronica, Christine Orengo, Veronica Vinciotti, Vinciotti, V., Xiaohui Liu, Swift, S., Kellam, P, Liu, Xiaohui, Vinciotti, V, Stephen Swift, Kellam, Paul, Orengo, C, Martin, Nigel, Nigel Martin   +27 more
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MOCA for Integrated Analysis of Gene Expression and Genetic Variation in Single Cells

Frontiers in Genetics, 2022
In cancer, somatic mutations occur continuously, causing cell populations to evolve. These somatic mutations result in the evolution of cellular gene expression patterns that can also change due to epigenetic modifications and environmental changes.
Jared Huzar, Jared Huzar, Hannah Kim, Hannah Kim, Sudhir Kumar, Sudhir Kumar, Sudhir Kumar, Sayaka Miura, Sayaka Miura   +8 more
openaire   +3 more sources

Analysis of MicroRNA Regulation and Gene Expression Variability in Single Cell Data

Journal of Personalized Medicine, 2022
MicroRNAs (miRNAs) regulate gene expression by binding to mRNAs, and thus reduce target gene expression levels and expression variability, also known as ‘noise’. Single-cell RNA sequencing (scRNA-seq) technology has been used to study miRNA and mRNA expression in single cells.
Wendao Liu, Noam Shomron
openaire   +2 more sources

Quantitative analysis of cell-type specific gene expression in the green alga Volvox carteri

, 2006
Nematollahi G, Kianianmomeni A, Hallmann A. Quantitative analysis of cell-type specific gene expression in the green alga Volvox carteri. BMC Genomics. 2006;7(1): 321.Background: The multicellular alga Volvox carteri possesses only two cell types: mortal,
Kianianmomeni Arash, Kianianmomeni, Arash, Hallmann Armin, Hallmann, Armin ; https://orcid.org/, Nematollahi, Ghazaleh, Nematollahi Ghazaleh   +5 more
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Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression [PDF]

, 2012
It is known that genetic variants can affect gene expression, but it is not yet completely clear through what mechanisms genetic variation mediate this expression.
Harry J M Groen, Veldink, Jan,, Meerman, Gerard J. te,, Groen, Harry JM, Westra, Harm-Jan,, Ophoff, Roel A.,, Wolfs, Marcel G.M.,, Snieder, Harold; id_orcid, Fehrmann, Rudolf S.N.,, Fu, J, Harry J. M. Groen (101726), Groen, H.J., Fu, Jingyuan, Westra, Harm Jan, Wolfs Marcel G. M., Patrick Deelen, Westra, Harm Jan; id_orcid, Wim A Buurman, van Heel David, Weersma, RK, Groen, Harry J.M.,, Marcel G M Wolfs, Marten H. Hofker (102396), Buurman Wim A., Patrick Deelen (187548), Jansen, R.C., Fehrmann, R.S., Weersma, Rinse K; id_orcid, Harm-Jan Westra, Jansen, Ritsert C, Wijmenga, Cisca, Meerman, GJT, Cisca Wijmenga, Gerard J Te Meerman, Franke, L, Fehrmann, RSN, Rensen, SSM, Wolfs, MGM, Jingyuan Fu (102399), Weersma, Rinse K.,, Rinse K. Weersma (131692), van den Berg, Leonard H, Harold Snieder (103613), Rensen, Sander S.M.,, Fu, Jingyuan,, Fehrmann, Rudolf S N, Rensen, Sander S M, van den Berg, L.H., Sander S. M. Rensen (187559), van den Berg Leonard H., Snieder Harold, Heel, David van,, Snieder, Harold,, Leonard H van den Berg, te Meerman, G.J., te Meerman Gerard J., Ritsert C Jansen, Wolfs, M.G., Deelen, Patrick, Snieder, H., Fu Jingyuan, Deelen, P., Cisca Wijmenga (32954), Weersma, R.K., Wijmenga, Cisca,, Roel A. Ophoff (155472), Wim A. Buurman (162734), Fu, Jingyuan; id_orcid, Franke, L., Groen, Hendricus, Ophoff, RA, Wolfs, Marcel GM, Wolfs, Marcel G M, Hofker Marten H., Buurman, WA, Leonard H. van den Berg (119440), van Heel, D., Westra, H-J, Hofker, MH, Lude Franke (102406), Buurman, W.A., Jan Veldink, Groen Harry J. M., Wijmenga, C., Wijmenga Cisca, Veldink, Jan, Meerman, Gerard J te, Lude Franke, Weersma, Rinse K, Jansen, Ritsert C.,, Sander S M Rensen, Wijmenga, C, Harm-Jan Westra (102374), Westra, H.J., Veldink, J., van den Berg, LH, Snieder, Harold, David van Heel (187571), Harold Snieder, David van Heel, Westra, Harm-Jan, Rudolf S. N. Fehrmann (87558), Westra Harm-Jan, Ophoff, Roel A, Deelen Patrick, Berg, Leonard H. van den,, Rensen Sander S. M., Fehrmann, Rudolf SN, Wijmenga, Cisca; id_orcid, Roel A Ophoff, Franke, Lude, Buurman, Wim A.,, Rensen, S.S.M.; id_orcid, Groen, HJM, Ritsert C. Jansen (32125), Deelen, Patrick,, van Heel, David, Rensen, Sander SM, Franke, Lude,, Rensen, S.S.M., Weersma Rinse K., Hofker, Marten H.,, Fehrmann Rudolf S. N., Franke Lude, Jan Veldink (187567), Hofker, M.H., van Heel, D, Snieder, H, Rudolf S N Fehrmann, Buurman, Wim A, Hofker, Marten H, Deelen, P, Marten H Hofker, Veldink Jan, Jingyuan Fu, Veldink, J, Rinse K Weersma, Marcel G. M. Wolfs (187544), Jansen Ritsert C., Ophoff, R.A., Jansen, RC, Gerard J. te Meerman (87570), te Meerman, Gerhardus, Ophoff Roel A., Groen, Hendricus; id_orcid, Fu, J.   +145 more
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Edge-weighting of gene expression graphs [PDF]

, 2009
In recent years, considerable research efforts have been directed to micro-array technologies and their role in providing simultaneous information on expression profiles for thousands of genes.
Kerr, Gráinne, Crane, Martin, DIMITRI PERRIN, HEATHER J. RUSKIN, Ruskin, Heather J., Perrin, Dimitri, MARTIN CRANE, GRAINNE KERR, Ruskin, Heather J   +8 more
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Dynamic expression of chromatin modifiers during developmental transitions in mouse preimplantation embryos [PDF]

, 2015
During mouse preimplantation development, major changes in cell fate are accompanied by extensive alterations of gene expression programs. Embryos first transition from a maternal to zygotic program and subsequently specify the pluripotent and the ...
Peters, Antoine H. F. M., Liu, Zichuan, Nestorov, Peter, Hotz, Hans-Rudolf   +3 more
core   +1 more source