Results 31 to 40 of about 667,361 (260)
Single-Cell RNA-Sequencing in Glioma
Current Oncology Reports, 2018 In this review, we seek to summarize the literature concerning the use of single-cell RNA-sequencing for CNS gliomas.Single-cell analysis has revealed complex tumor heterogeneity, subpopulations of proliferating stem-like cells and expanded our view of tumor microenvironment influence in the disease process.
Eli, Johnson +3 more
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Review of Single-Cell RNA Sequencing in the Heart [PDF]
International Journal of Molecular Sciences, 2020 Single-cell RNA sequencing (scRNA-seq) technology is a powerful, rapidly developing tool for characterizing individual cells and elucidating biological mechanisms at the cellular level. Cardiovascular disease is one of the major causes of death worldwide and its precise pathology remains unclear.
Shintaro Yamada, Seitaro Nomura
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Revolutionizing immunology with single-cell RNA sequencing [PDF]
Cellular & Molecular Immunology, 2019 The immune system is composed of a complex hierarchy of cell types that protect the organism against disease and maintain homeostasis. Identifying heterogeneity of immune cells is the key to understanding the immune system. Advanced single-cell RNA sequencing (scRNA-seq) technologies are revolutionizing our ability to study immunology.
Haide, Chen, Fang, Ye, Guoji, Guo
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The Technology and Biology of Single-Cell RNA Sequencing [PDF]
Molecular Cell, 2015 The differences between individual cells can have profound functional consequences, in both unicellular and multicellular organisms. Recently developed single-cell mRNA-sequencing methods enable unbiased, high-throughput, and high-resolution transcriptomic analysis of individual cells. This provides an additional dimension to transcriptomic information
Kolodziejczyk, Aleksandra A. +4 more
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Single-cell isolation by a modular single-cell pipette for RNA-sequencing [PDF]
Lab on a Chip, 2016 We report a modular single-cell pipette (mSCP), consisting of an air-displacement pipette (ADP), ADP-Tips, and a SCP-Tip, and its application in single-cell isolation for RNA-sequencing.
Kai Zhang +6 more
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Computational and Structural Biotechnology Journal, 2023 Obesity affects the function of multiple organs/tissues including the exocrine organ salivary glands. However, the effects of obesity on transcriptomes and cell compositions in the salivary glands have yet been studied by bulk RNA-sequencing and single ...
Heping Huang +5 more
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Continual learning approaches for single cell RNA sequencing data
Scientific Reports, 2023 Single-cell RNA sequencing data is among the most interesting and impactful data of today and the sizes of the available datasets are increasing drastically.
Gorkem Saygili, Busra OzgodeYigin
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Single Cell RNA-Sequencing for the Study of Atherosclerosis
Journal of Lipid and Atherosclerosis, 2019 Atherosclerosis is a major cause of coronary artery disease and stroke. A massive and new type of data has finally arrived in the field of atherosclerosis: single cell RNA sequencing (scRNAseq). Recently, scRNAseq has been successfully applied to the study of atherosclerosis to identify previously uncharacterized cell populations.
Morteza Chalabi Hajkarim, Kyoung Jae Won
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Neuroendocrinology of the lung revealed by single cell RNA sequencing
eLife, 2022 ABSTRACT Pulmonary neuroendocrine cells (PNECs) are sensory epithelial cells that transmit airway status to the brain via sensory neurons and locally via CGRP and GABA. Several other neuropeptides and neurotransmitters have been detected in various species, but the number, targets, functions, and conservation of PNEC signals are largely
Christin S Kuo +7 more
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From bulk, single-cell to spatial RNA sequencing
International Journal of Oral Science, 2021 RNA sequencing (RNAseq) can reveal gene fusions, splicing variants, mutations/indels in addition to differential gene expression, thus providing a more complete genetic picture than DNA sequencing.
Xinmin Li, Cun-Yu Wang
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