Results 171 to 180 of about 1,166,241 (315)

QCatch: a framework for quality control assessment and analysis of single-cell sequencing data. [PDF]

Bioinformatics
Gao Y, He D, Patro R.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Insights gained from single-cell sequencing analysis of ischemic stroke. [PDF]

Front Cell Dev Biol
Mei Y, Guan T, Fu L, Kong J, Lv Y.
europepmc   +1 more source

Sequencing Games with Controllable Processing Time

In this paper we study a class of cooperative sequencing games that arise from sequencing situations in which the processing times are not fixed.We show that these games are balanced by obtaining two core elements that depend only on the optimal schedule
Velzen, S. van
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Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Editorial: Statistical and computational methods for single-cell sequencing analysis

Frontiers in Genetics, 2023
Lin Hou, Zhicheng Ji, Jingshu Wang, Jichun Xie, Jichun Xie   +4 more
doaj   +1 more source

Unraveling the significance of decorin in endometriosis development through single cell sequencing and experimental approaches. [PDF]

PLoS One
Chen G, Li W, Liu L, Wang Y.
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Research Progress of Interstitial Lung Disease Based on Single-Cell Sequencing Technology. [PDF]

Can Respir J
Li S, Zhou T, Zhang J, Zhang L, Li Q, Li B, Dai J, Yu R, Li Y, Li S.   +9 more
europepmc   +1 more source

Single-Cell optimisation in the analysis of microbial communities

openL’utilizzo della tecnica di single-cell genome sequencing è fondamentale per l’analisi di sistemi biologici complessi, come le comunità microbiche, con il fine di approfondire l’eterogeneità che le caratterizza e comprendere i meccanismi ...
PERETTI, ALESSANDRO
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