Results 31 to 40 of about 173,386 (236)

Prospects for single-particle imaging at XFELs [PDF]

Digest of the LEOS Summer Topical Meetings Biophotonics/Optical Interconnects and VLSI Photonics/WBM Microcavities, 2004., 2004
X-ray free-electron lasers will produce pulses of X-rays that are 10 orders of magnitude brighter than today's undulator sources at synchrotrons. This may enable atomic resolution imaging of single macromolecules.
Chapman, H N, Hau-Riege, S P, London, R A, Marchesini, S, Noy, A, Szoke, A, Szoke, H, Ingerman, E, Hajdu, J, Huldt, G, Howells, M R, He, H, Spence, J H, Weierstall, U   +13 more
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Modular Imaging Scaffold for Single-Particle Electron Microscopy

ACS Nano, 2021
Technological breakthroughs in electron microscopy (EM) have made it possible to solve structures of biological macromolecular complexes and to raise novel challenges, specifically related to sample preparation and heterogeneous macromolecular assemblies such as DNA-protein, protein-protein, and membrane protein assemblies.
Aissaoui, Nesrine, Him, Josephine Lai Kee, Mills, Allan, Declerck, Nathalie, Morichaud, Zakia, Brodolin, Konstantin, Baconnais, Sonia, Le Cam, Eric, Charbonnier, Jean-Baptiste, Sounier, Rémy, Granier, Sébastien, Ropars, Virginie, Bron, Patrick, Bellot, Gaetan   +13 more
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Microlens-Assisted Light-Scattering Imaging of Plasmonic Nanoparticles at the Single Particle Level

Biosensors, 2023
We present a microlens-assisted imaging approach to record the scattering light of plasmonic nanoparticles at the single particle level. The microlens can significantly enhance the backscattering of visible light from individual plasmonic nanoparticles ...
Pengcheng Zhang, Tingting Zhan, Sha Xue, Hui Yang   +3 more
doaj   +1 more source

Single Particle Imaging with FEL Using Photon Correlations [PDF]

, 2020
AbstractScattering experiments with femtosecond high-intensity free-electron laser pulses provide a new route to macromolecular structure determination without the need for crystallization at low material usage. In these experiments, the X-ray pulses are scattered with high repetition on a stream of identical single biomolecules and the scattered ...
von Ardenne, Benjamin, Grubmüller, Helmut, Salditt, Tim, Egner, Alexander, Luke, D. Russell   +4 more
openaire   +4 more sources

Megahertz single-particle imaging at the European XFEL [PDF]

Communications Physics, 2020
AbstractThe emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by superconducting accelerator technology enables the measurement of significantly more experimental data per day than was previously possible. The European XFEL is expected to provide 27,000 pulses per second, over two orders of magnitude more than any other XFEL.
Egor Sobolev, Sergei Zolotarev, Klaus Giewekemeyer, Johan Bielecki, Kenta Okamoto, Hemanth K. N. Reddy, Jakob Andreasson, Kartik Ayyer, Imrich Barak, Sadia Bari, Anton Barty, Richard Bean, Sergey Bobkov, Henry N. Chapman, Grzegorz Chojnowski, Benedikt J. Daurer, Katerina Dörner, Tomas Ekeberg, Leonie Flückiger, Oxana Galzitskaya, Luca Gelisio, Steffen Hauf, Brenda G. Hogue, Daniel A. Horke, Ahmad Hosseinizadeh, Vyacheslav Ilyin, Chulho Jung, Chan Kim, Yoonhee Kim, Richard A. Kirian, Henry Kirkwood, Olena Kulyk, Jochen Küpper, Romain Letrun, N. Duane Loh, Kristina Lorenzen, Marc Messerschmidt, Kerstin Mühlig, Abbas Ourmazd, Natascha Raab, Andrei V. Rode, Max Rose, Adam Round, Takushi Sato, Robin Schubert, Peter Schwander, Jonas A. Sellberg, Marcin Sikorski, Alessandro Silenzi, Changyong Song, John C. H. Spence, Stephan Stern, Jolanta Sztuk-Dambietz, Anthon Teslyuk, Nicusor Timneanu, Martin Trebbin, Charlotte Uetrecht, Britta Weinhausen, Garth J. Williams, P. Lourdu Xavier, Chen Xu, Ivan A. Vartanyants, Victor S. Lamzin, Adrian Mancuso, Filipe R. N. C. Maia   +64 more
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Solution of the phase problem for coherent scattering from a disordered system of identical particles

New Journal of Physics, 2013
While the implementation of single-particle coherent diffraction imaging for non-crystalline particles is complicated by current limitations on photon flux, hit rate and sample delivery, the concept of many-particle coherent diffraction imaging offers an
R P Kurta, R Dronyak, M Altarelli, E Weckert, I A Vartanyants   +4 more
doaj   +1 more source

The structure of tick-borne encephalitis virus determined at X-ray free-electron lasers. Simulations

Journal of Synchrotron Radiation, 2023
The study of virus structures by X-ray free-electron lasers (XFELs) has attracted increased attention in recent decades. Such experiments are based on the collection of 2D diffraction patterns measured at the detector following the application of ...
Dameli Assalauova, Ivan A. Vartanyants
doaj   +1 more source

Selection and orientation of different particles in single particle imaging [PDF]

Journal of Structural Biology, 2013
The short pulses of X-ray free electron lasers can produce diffraction patterns with structural information before radiation damage destroys the particle. The particles are injected into the beam in random orientations and they should be identical. However, in real experimental conditions it is not always possible to have identical particles.
Tegze, Miklós, Bortel, Gábor
openaire   +3 more sources

Complex imaging of phase domains by deep neural networks

IUCrJ, 2021
The reconstruction of a single-particle image from the modulus of its Fourier transform, by phase-retrieval methods, has been extensively applied in X-ray structural science.
Longlong Wu, Pavol Juhas, Shinjae Yoo, Ian Robinson   +3 more
doaj   +1 more source

Emerging Themes in CryoEM─Single Particle Analysis Image Processing

Chemical Reviews, 2022
Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is an interdisciplinary field that takes advantage of advances in biochemistry, physics, and image processing, among other disciplines. Innovations in these three basic pillars have contributed to the boosting of CryoEM in the past decade.
Vilas, Jose Luis, Carazo, Jose Maria, Sorzano, Carlos Oscar S.   +2 more
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