Results 11 to 20 of about 495,951 (309)

The linac coherent light source single particle imaging road map [PDF]

Structural Dynamics, 2015
Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so ...
A. Aquila, A. Barty, C. Bostedt, S. Boutet, G. Carini, D. dePonte, P. Drell, S. Doniach, K. H. Downing, T. Earnest, H. Elmlund, V. Elser, M. Gühr, J. Hajdu, J. Hastings, S. P. Hau-Riege, Z. Huang, E. E. Lattman, F. R. N. C. Maia, S. Marchesini, A. Ourmazd, C. Pellegrini, R. Santra, I. Schlichting, C. Schroer, J. C. H. Spence, I. A. Vartanyants, S. Wakatsuki, W. I. Weis, G. J. Williams   +29 more
doaj   +8 more sources

Optimizing aerodynamic lenses for single-particle imaging [PDF]

Journal of Aerosol Science, 2017
A numerical simulation infrastructure capable of calculating the flow of gas and the trajectories of particles through an aerodynamic lens injector is presented.
Awel, Salah, Horke, Daniel A., Küpper, Jochen, Roth, Nils   +3 more
core   +6 more sources

Ultrafast Single-Particle Imaging with Intense X-Ray Pulses

CHIMIA, 2022
Ultrafast single-particle imaging with intense x-ray pulses from free-electron laser sources provides a new approach for visualizing structure and dynamics on the nanoscale. After a short introduction to the novel free-electron laser sources and methods,
Zhibin Sun, Andre Al Haddad, Sven Augustin, Gregor Knopp, Jonas Knurr, Kirsten Schnorr, Christoph Bostedt   +6 more
doaj   +3 more sources

An advanced workflow for single-particle imaging with the limited data at an X-ray free-electron laser [PDF]

IUCrJ, 2020
An improved analysis for single-particle imaging (SPI) experiments, using the limited data, is presented here. Results are based on a study of bacteriophage PR772 performed at the Atomic, Molecular and Optical Science instrument at the Linac Coherent ...
Dameli Assalauova, Young Yong Kim, Sergey Bobkov, Ruslan Khubbutdinov, Max Rose, Roberto Alvarez, Jakob Andreasson, Eugeniu Balaur, Alice Contreras, Hasan DeMirci, Luca Gelisio, Janos Hajdu, Mark S. Hunter, Ruslan P. Kurta, Haoyuan Li, Matthew McFadden, Reza Nazari, Peter Schwander, Anton Teslyuk, Peter Walter, P. Lourdu Xavier, Chun Hong Yoon, Sahba Zaare, Viacheslav A. Ilyin, Richard A. Kirian, Brenda G. Hogue, Andrew Aquila, Ivan A. Vartanyants   +27 more
doaj   +2 more sources

A predicted model-aided one-step classification–multireconstruction algorithm for X-ray free-electron laser single-particle imaging [PDF]

IUCrJ
Ultrafast, high-intensity X-ray free-electron lasers can perform diffraction imaging of single protein molecules. Various algorithms have been developed to determine the orientation of each single-particle diffraction pattern and reconstruct the 3D ...
Zhichao Jiao, Zhi Geng, Wei Ding
doaj   +2 more sources

Recovery of undamaged electron-density maps in the presence of damage-induced partial coherence in single-particle imaging [PDF]

IUCrJ, 2020
Resolving the electronic structure of single biological molecules in their native state was among the primary motivations behind X-ray free-electron lasers. The ultra-short pulses they produce can outrun the atomic motion induced by radiation damage, but
Alexander Kozlov, Timur E. Gureyev, David M. Paganin, Andrew V. Martin, Carl Caleman, Harry M. Quiney   +5 more
doaj   +2 more sources

Effects of radiation damage and inelastic scattering on single-particle imaging of hydrated proteins with an X-ray Free-Electron Laser [PDF]

Scientific Reports, 2021
We present a computational case study of X-ray single-particle imaging of hydrated proteins on an example of 2-Nitrogenase–Iron protein covered with water layers of various thickness, using a start-to-end simulation platform and experimental parameters ...
Juncheng E, Michal Stransky, Zoltan Jurek, Carsten Fortmann-Grote, Libor Juha, Robin Santra, Beata Ziaja, Adrian P. Mancuso   +7 more
doaj   +2 more sources

Expansion-maximization-compression algorithm with spherical harmonics for single particle imaging with x-ray lasers [PDF]

, 2016
In 3D single particle imaging with X-ray free-electron lasers, particle orientation is not recorded during measurement but is instead recovered as a necessary step in the reconstruction of a 3D image from the diffraction data.
Julien Flamant, Nicolas Le Bihan, Andrew V. Martin, Jonathan H. Manton   +3 more
openalex   +4 more sources

A predicted model-aided reconstruction algorithm for X-ray free-electron laser single-particle imaging [PDF]

IUCrJ
Ultra-intense, ultra-fast X-ray free-electron lasers (XFELs) enable the imaging of single protein molecules under ambient temperature and pressure.
Zhichao Jiao, Yao He, Xingke Fu, Xin Zhang, Zhi Geng, Wei Ding   +5 more
doaj   +2 more sources

Single-particle imaging without symmetry constraints at an X-ray free-electron laser [PDF]

IUCrJ, 2018
The analysis of a single-particle imaging (SPI) experiment performed at the AMO beamline at LCLS as part of the SPI initiative is presented here. A workflow for the three-dimensional virus reconstruction of the PR772 bacteriophage from measured single ...
Max Rose, Sergey Bobkov, Kartik Ayyer, Ruslan P. Kurta, Dmitry Dzhigaev, Young Yong Kim, Andrew J. Morgan, Chun Hong Yoon, Daniel Westphal, Johan Bielecki, Jonas A. Sellberg, Garth Williams, Filipe R.N.C. Maia, Olexander M. Yefanov, Vyacheslav Ilyin, Adrian P. Mancuso, Henry N. Chapman, Brenda G. Hogue, Andrew Aquila, Anton Barty, Ivan A. Vartanyants   +20 more
doaj   +2 more sources