Results 31 to 40 of about 58,343 (263)

Superconducting single-photon detectors fabricated via a focused electron beam-induced deposition process

AIP Advances, 2023
Superconducting detectors have become essential devices for high-performance single-photon counting over a wide wavelength range with excellent time resolution.
Stephan Steinhauer, Adrian Iovan, Samuel Gyger, Val Zwiller   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Photon-Counting Underwater Optical Wireless Communication for Reliable Video Transmission Using Joint Source-Channel Coding Based on Distributed Compressive Sensing

Sensors, 2019
To achieve long-distance underwater optical wireless communication, a single photon detector with single photon limit sensitivity is used to detect the optical signal at the receiver.
Zhu Hong, Qiurong Yan, Zihang Li, Ting Zhan, Yuhao Wang   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Heterodyne spectroscopy with superconducting single-photon detector

EPJ Web of Conferences, 2017
We demonstrate successful operation of a Superconducting Single Photon Detector (SSPD) as the core element in a heterodyne receiver. Irradiating the SSPD by both a local oscillator power and signal power simultaneously, we observed beat signal at the ...
Lobanov Yu.V., Shcherbatenko M.L., Semenov A.V., Kovalyuk V.V., Korneev A.A., Goltsman G.N.   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

High-quality photon-limited imaging through dynamic and complex scattering media with a single-photon detector [PDF]

APL Photonics
Recent advances in single-photon detectors have enabled low-light detection in diverse applications ranging from biological imaging to astronomy. However, it remains a challenge to realizing high-quality optical imaging through dynamic and complex ...
Yining Hao, Yang Peng, Tianshun Zhang, Wen Chen   +3 more
doaj   +1 more source

Quantum calibrations traceable through classical radiometry

Measurement: Sensors, 2021
A system for calibrating single photon detector efficiency that is traceable to the SI through a state-of-the-art classical optical fibre radiometer has been developed and is in the process of being vetted as a calibration service at the National ...
Michelle Stephens, Malcolm G. White, Thomas Gerrits, Nathan A. Tomlin, John H. Lehman   +4 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Photon-Counting Spectrometers Based on Superconducting Nanowire Single-Photon Detectors

Electromagnetic Science
Optical spectrum analysis provides a wealth of information about the physical world. Throughout the development of optical spectrum analysis, sensitivity has been one of the major topics and has become essential in applications dealing with faint light ...
Mingzhong Hu, Jingyuan Zheng, Kaiyu Cui, Wei Zhang, Yidong Huang   +4 more
doaj   +1 more source