Results 31 to 40 of about 8,991,121 (239)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Derivation of OCC Modulator for Grid-Tied Single-Stage Buck-Boost Inverter Operating in the Discontinuous Conduction Mode

open access: yesEnergies, 2020
This paper is concerned with the derivation of a one-cycle controller for driving a single-stage buck-boost DC-AC micro-inverter in grid-tied applications.
Ben Zhao   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Modulation Techniques for a Modified Three-Phase Quasi-Switched Boost Inverter With Common-Mode Voltage Reduction

open access: yesIEEE Access, 2020
In a single-stage buck-boost quasi-switched boost inverter (qSBI), the shoot-through state insertion causes high amplitude common-mode voltage. Consequently, the qSBI becomes less attractive in transformerless photovoltaic (PV) systems.
Truong-Duy Duong   +5 more
doaj   +1 more source

A New Non-Isolated Active Quasi Z-Source Multilevel Inverter With High Gain Boost

open access: yesIEEE Access, 2023
This paper proposes a three-level diode clamped active impedance source inverter (AIS-TLI) based on the quasi Z-source inverter (qZSI). Apart from having minimal components and the inherent benefits of three-level qZSIs, such as single-stage buck-boost ...
Sohrab Naderi, Hasan Rastegar
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Capacitor Bank Voltage Equilibrium for MPPT in Single-Phase Single-Stage Five-Level Inverter for PV-Grid Application [PDF]

open access: yes, 2015
Single-phase single-stage PV-Grid system using a five-level inverter has been investigated. Some of integration systems used two-stage converters, while others used single-stage converter. However, two-stage converters had a very complicated problem. The
Wijaya, F. Danang   +2 more
core   +2 more sources

A Three-Level Single Stage A-Source Inverter With the Ability to Generate Active Voltage Vector During Shoot-Through State

open access: yesIEEE Access, 2022
Single-stage boosting capability of impedance network (IN) inverters makes this family of inverters an attractive choice for DC/AC applications with low input DC voltage.
Mohammad Reza Kheyrati   +4 more
doaj   +1 more source

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