Results 41 to 50 of about 15,513 (299)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Micro Inverter Grid Connected for PV Application Based on SEPIC Differential Inverter [PDF]

SVU-International Journal of Engineering Sciences and Applications
The problem of shading in photovoltaic systems has occupied a large part of the researchers' interests, and for this reason, the Micro-inverter (MI) is used as the solution, and the idea of manufacturing them depends on installing a small inverter with a
Mohamed Ismeil, Hany S. Hussein, Mahmoud Nasrallah   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Inversor cinco níveis em corrente para o acionamento de motores elétricos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2013.Neste trabalho apresenta-se um estudo sobre inversores trifásicos multiníveis em corrente, para o ...
Dupczak, Bruno Scortegagna
core  

A New Single Stage Common Ground Five-Switch Boosting Transformerless Inverter

IEEE Access
Transformerless inverters (TIs) are widely employed in photovoltaic (PV) applications due to their cost-effectiveness, compact size, low weight, and high efficiency. However, the absence of electrical isolation can result in ground leakage current due to
Dai-van Vo, Khai M. Nguyen, Tan-Tai Tran, Van-Cuong Bui, Young-Cheol Lim, Joon-Ho Choi   +5 more
doaj   +1 more source

A Three-Level Single Stage A-Source Inverter With the Ability to Generate Active Voltage Vector During Shoot-Through State

IEEE Access, 2022
Single-stage boosting capability of impedance network (IN) inverters makes this family of inverters an attractive choice for DC/AC applications with low input DC voltage.
Mohammad Reza Kheyrati, Amirhossein Rajaei, Vahid Moradzadeh Tehrani, Ghazal Mirzavand, Mahdi Shahparasti   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Novel Transformerless Single-Stage Grid-Connected Solar Inverter

, 2023
A novel tranformerless single-stage grid-connected solar inverter with a combination of a bidirectional dc/dc boost converter followed by a flyback inductor inverter is proposed.
Akshay Kumar Rathore (11720225), Manish Verma (8417652), Sivanagaraju Gangavarapu (16981881)   +2 more
core   +1 more source

Modulation Techniques for a Modified Three-Phase Quasi-Switched Boost Inverter With Common-Mode Voltage Reduction

IEEE Access, 2020
In a single-stage buck-boost quasi-switched boost inverter (qSBI), the shoot-through state insertion causes high amplitude common-mode voltage. Consequently, the qSBI becomes less attractive in transformerless photovoltaic (PV) systems.
Truong-Duy Duong, Minh-Khai Nguyen, Tan-Tai Tran, Young-Cheol Lim, Joon-Ho Choi, Caisheng Wang   +5 more
doaj   +1 more source

A New Non-Isolated Active Quasi Z-Source Multilevel Inverter With High Gain Boost

IEEE Access, 2023
This paper proposes a three-level diode clamped active impedance source inverter (AIS-TLI) based on the quasi Z-source inverter (qZSI). Apart from having minimal components and the inherent benefits of three-level qZSIs, such as single-stage buck-boost ...
Sohrab Naderi, Hasan Rastegar
doaj   +1 more source