Results 201 to 210 of about 367,400 (264)

Directed assembly of single-stranded DNA fragments for data storage via protein-free catalytic splint ligation. [PDF]

Nucleic Acids Res
Mendonsa G, Chari S, Bao M, Herdendorf B, Reddy A.   +4 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Molecular Characterization and Protective Efficacy of a Novel Protein (EnSSB) Containing a Single-Stranded DNA-Binding Domain from <i>Eimeria necatrix</i>. [PDF]

Animals (Basel)
Zhu Y, Liu D, Wang L, Feng Q, Xue N, Hou Z, Xu J, Tao J.   +7 more
europepmc   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

Single-Stranded DNA Gap Accumulation Is a Functional Biomarker for USP1 Inhibitor Sensitivity. [PDF]

Cancer Res
da Costa AA, Somuncu O, Ravindranathan R, Mukkavalli S, Martignetti DB, Nguyen H, Jiao Y, Lamarre BP, Sadatrezaei G, Moreau L, Liu J, Iyer DR, Lazaro JB, Shapiro GI, Parmar K, D'Andrea AD.   +15 more
europepmc   +1 more source

Stabilization of a single-stranded DNA of adeno-associated virus by inverted terminal repeats. [PDF]

Sci Rep
Yuan Y, Higashiyama K, Ito-Kudo E, Masumi-Koizumi K, Yusa K, Uchida K.   +5 more
europepmc   +1 more source

Single-molecule fluorescence reveals the DNA unwinding mechanism of mitochondrial helicase TWINKLE and its interplay with single-stranded DNA-binding proteins. [PDF]

Nucleic Acids Res
Wang HY, Lee YY, Chien PJ, Tsai WA, Sun PJ, Wang LT, Wu CC, Fan HF.   +7 more
europepmc   +1 more source

The concentration of single-stranded DNA-binding proteins is a critical factor in recombinase polymerase amplification (RPA), as revealed by insights from an open-source system. [PDF]

PeerJ
Cordoba-Andrade F, Peralta-Castro A, García-Medel PL, Castro-Torres E, Gonzalez-Gonzalez R, Castro-Lara AY, Mora Garduño JD, Raygoza CD, Baruch-Torres N, Peñafiel-Ayala A, Diaz-Quezada C, Cardona-Felix CS, Guzman Chavez F, Trasviña-Arenas CH, Sotelo-Mundo RR, Xoconostle-Cazares B, Martínez-Antonio A, Brieba de Castro LG.   +17 more
europepmc   +1 more source

Fast and efficient method for parallel construction of targeted exome and methylome single-stranded DNA sequencing libraries. [PDF]

Sci Rep
Kim E, An S, Ahn H, Lim J, Kim SK, Park AK.   +5 more
europepmc   +1 more source

Super-resolution imaging reveals nucleolar encapsulation by single-stranded DNA. [PDF]

J Cell Sci
Maki K, Fukute J, Adachi T.
europepmc   +1 more source