Results 11 to 20 of about 12,921,630 (316)
, 2021 Cells are the most fundamental building block of all living organisms. The investigation of any type of disease mechanism and its progression still remains challenging due to cellular heterogeneity characteristics and physiological state of cells in a ...
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Single-cell profiling of transcriptome and histone modifications with EpiDamID [PDF]
, 2022 Recent advances in single-cell sequencing technologies have enabled simultaneous measurement of multiple cellular modalities, but the combined detection of histone post-translational modifications and transcription at single-cell resolution has remained ...
Rang, Franka J +14 more
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Annual Review of Biomedical Data Science, 2023 Single-cell RNA sequencing methods have led to improved understanding of the heterogeneity and transcriptomic states present in complex biological systems. Recently, the development of novel single-cell technologies for assaying additional modalities, specifically genomic, epigenomic, proteomic, and spatial data, allows for unprecedented insight into ...
Flynn, Emily +2 more
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Information and the single cell
Current Opinion in Neurobiology, 2021 Understanding the evolution of cognition requires an understanding of the costs and benefits of neural computation. This requires analysis of neuronal circuitry in terms of information-processing efficiency, ultimately cashed out in terms of ATP expenditures relative to adaptive problem-solving abilities.
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Role of Protein Arginine Methyltransferases and Inflammation in Muscle Pathophysiology
Frontiers in Physiology, 2021 Arginine methylation mediated by protein arginine methyltransferases (PRMTs) is a post-translational modification of both histone and non-histone substrates related to diverse biological processes.
Hyun-Kyung So +4 more
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Methods, Challenges and Potentials of Single Cell RNA-seq [PDF]
, 2012 RNA-sequencing (RNA-seq) has become the tool of choice for transcriptomics. Several recent studies demonstrate its successful adaption to single cell analysis. This allows new biological insights into cell differentiation, cell-to-cell variation and gene
Daniel Hebenstreit, Hebenstreit, Daniel
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Nature Communications, 2023 Histone H2A monoubiquitination (H2Aub1) functions as a conserved posttranslational modification in eukaryotes to maintain gene expression and guarantee cellular identity.
Yu Zhang +10 more
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Journal of Advanced Research, 2021 Introduction: Environmental stress is both a major force of natural selection and a prime factor affecting crop qualities and yields. The impact of the GRAS [gibberellic acid-insensitive (GAI), repressor of GA1–3 mutant (RGA), and scarecrow (SCR)] family
Moyang Liu +6 more
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Plant single-cell and single-cell-type metabolomics
Trends in Plant Science, 2014 In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding ...
Biswapriya B, Misra +2 more
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Clinical and Translational Medicine, 2022 Background The number of patients receiving anaesthesia is increasing, but the impact of general anaesthesia on the patient's immune system remains unclear.
Yang‐Yang Wang +10 more
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