Results 11 to 20 of about 3,900,612 (318)

Arginine methylation as a key post-translational modification in skeletal muscle homeostasis: a review [PDF]

open access: yesPrecision and Future Medicine, 2019
Arginine methylation mediated by protein arginine methyltransferases (PRMTs) has emerged as a key post-translational modification of histone or nonhistone substrates.
Hyebeen Kim   +2 more
doaj   +1 more source

Exploring functional protein covariation across single cells using nPOP

open access: yesGenome Biology, 2022
Background Many biological processes, such as cell division cycle and drug resistance, are reflected in protein covariation across single cells. This covariation can be quantified and interpreted by single-cell mass spectrometry with sufficiently high ...
Andrew Leduc   +4 more
doaj   +1 more source

Role of Protein Arginine Methyltransferases and Inflammation in Muscle Pathophysiology

open access: yesFrontiers in Physiology, 2021
Arginine methylation mediated by protein arginine methyltransferases (PRMTs) is a post-translational modification of both histone and non-histone substrates related to diverse biological processes.
Hyun-Kyung So   +4 more
doaj   +1 more source

Histone H2A monoubiquitination marks are targeted to specific sites by cohesin subunits in Arabidopsis

open access: yesNature Communications, 2023
Histone H2A monoubiquitination (H2Aub1) functions as a conserved posttranslational modification in eukaryotes to maintain gene expression and guarantee cellular identity.
Yu Zhang   +10 more
doaj   +1 more source

A multilayered cross-species analysis of GRAS transcription factors uncovered their functional networks in plant adaptation to the environment

open access: yesJournal of Advanced Research, 2021
Introduction: Environmental stress is both a major force of natural selection and a prime factor affecting crop qualities and yields. The impact of the GRAS [gibberellic acid-insensitive (GAI), repressor of GA1–3 mutant (RGA), and scarecrow (SCR)] family
Moyang Liu   +6 more
doaj   +1 more source

An atlas of dynamic peripheral blood mononuclear cell landscapes in human perioperative anaesthesia/surgery

open access: yesClinical and Translational Medicine, 2022
Background The number of patients receiving anaesthesia is increasing, but the impact of general anaesthesia on the patient's immune system remains unclear.
Yang‐Yang Wang   +10 more
doaj   +1 more source

Methods, Challenges and Potentials of Single Cell RNA-seq [PDF]

open access: yes, 2012
RNA-sequencing (RNA-seq) has become the tool of choice for transcriptomics. Several recent studies demonstrate its successful adaption to single cell analysis. This allows new biological insights into cell differentiation, cell-to-cell variation and gene
Daniel Hebenstreit, Hebenstreit, Daniel
core   +1 more source

Plant single-cell and single-cell-type metabolomics

open access: yesTrends in Plant Science, 2014
In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding ...
Biswapriya B, Misra   +2 more
openaire   +3 more sources

Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin

open access: yesNature Communications, 2023
Force transmission at integrin-based adhesions is important for cell migration and mechanosensing. Talin is an essential focal adhesion (FA) protein that links F-actin to integrins.
Sawako Yamashiro   +5 more
doaj   +1 more source

Single-Cell Nanosurgery [PDF]

open access: yes, 2013
This chapter explains the steps necessary to perform laser surgery upon single adherent mammalian cells, where individual organelles are extracted from the cells by optical tweezers and the cells are monitored post-surgery to check their viability. Single-cell laser nanosurgery is used in an increasing range of methodologies because it offers great ...
Maxwell B, Zeigler, Daniel T, Chiu
openaire   +2 more sources

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