Results 21 to 30 of about 3,900,612 (318)

Rehabilitation and the single cell [PDF]

open access: yesCurrent Opinion in Cell Biology, 2007
Cellular damage triggers rapid resealing of the plasma membrane and repair of the cortical cytoskeleton. Plasma membrane resealing results from calcium-dependent fusion of membranous organelles and the plasma membrane at the site of the damage.
William M, Bement   +4 more
openaire   +2 more sources

A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks

open access: yeseLife, 2022
Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends.
Danielle Holz   +5 more
doaj   +1 more source

Single-Cell Physiology [PDF]

open access: yesAnnual Review of Biophysics, 2015
Single-cell techniques have a long history of unveiling fundamental paradigms in biology. Recent improvements in the throughput, resolution, and availability of microfluidics, computational power, and genetically encoded fluorescence have led to a modern renaissance in microbial physiology.
Taheri-Araghi, Sattar   +4 more
openaire   +4 more sources

Single-Cell Multiomics

open access: yesAnnual Review of Biomedical Data Science, 2023
Single-cell RNA sequencing methods have led to improved understanding of the heterogeneity and transcriptomic states present in complex biological systems. Recently, the development of novel single-cell technologies for assaying additional modalities, specifically genomic, epigenomic, proteomic, and spatial data, allows for unprecedented insight into ...
Flynn, Emily   +2 more
openaire   +4 more sources

The inhibition of chloride intracellular channel 1 enhances Ca2+ and reactive oxygen species signaling in A549 human lung cancer cells

open access: yesExperimental and Molecular Medicine, 2019
Cancer: chloride transport protein protects tumors A chloride channel, a membrane protein involved in chloride transport, indirectly regulates calcium signaling to protect cancer cells from free radicals and DNA damage.
Jae-Rin Lee   +5 more
doaj   +1 more source

Genome-wide identification of nitrate transporter genes from Spirodela polyrhiza and characterization of SpNRT1.1 function in plant development

open access: yesFrontiers in Plant Science, 2022
Nitrate transporter (NRT) genes that participate in nitrate transport and distribution are indispensable for plant growth, development, and stress tolerance.
Mengli Lv   +3 more
doaj   +1 more source

Quantitative investigation of calcimimetic R568 on beta cell adhesion and mechanics using AFM single-cell force spectroscopy [PDF]

open access: yes, 2014
In this study we use a novel approach to quantitatively investigate mechanical and interfacial properties of clonal β-cells using AFM-Single Cell Force Spectroscopy (SCFS). MIN6 cells were incubated for 48hrs with 0.5mM Ca2+ ± the calcimimetic R568 (1μM).
Younis, Mustafa Y.G.   +5 more
core   +1 more source

The role of urinary pteridines as disease biomarkers

open access: yesPteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Single-cell states in the estrogen response of breast cancer cell lines [PDF]

open access: yes, 2014
Estrogen responsive breast cancer cell lines have been extensively studied to characterize transcriptional patterns in hormone-responsive tumors. Nevertheless, due to current technological limitations, genome-wide studies have typically been limited to ...
Andrea Gamba   +49 more
core   +1 more source

IGDB-DuLab/Single-cell-phenotype-analysis: SCPA_code

open access: yes, 2022
This repository contains the source code used in our study titled "Defect-Buffering Cellular Plasticity Increases Robustness of Metazoan Embryogenesis". The provided scripts allow quantification and phenotypic determination of six types of developmental ...
IGDB-DuLab
core   +1 more source

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