Results 21 to 30 of about 13,531,309 (317)

Arginine methylation as a key post-translational modification in skeletal muscle homeostasis: a review [PDF]

open access: yesPrecision and Future Medicine, 2019
Arginine methylation mediated by protein arginine methyltransferases (PRMTs) has emerged as a key post-translational modification of histone or nonhistone substrates.
Hyebeen Kim   +2 more
doaj   +1 more source

Information and the single cell

open access: yesCurrent Opinion in Neurobiology, 2021
Understanding the evolution of cognition requires an understanding of the costs and benefits of neural computation. This requires analysis of neuronal circuitry in terms of information-processing efficiency, ultimately cashed out in terms of ATP expenditures relative to adaptive problem-solving abilities.
openaire   +3 more sources

Methods, Challenges and Potentials of Single Cell RNA-seq [PDF]

open access: yes, 2012
RNA-sequencing (RNA-seq) has become the tool of choice for transcriptomics. Several recent studies demonstrate its successful adaption to single cell analysis. This allows new biological insights into cell differentiation, cell-to-cell variation and gene
Daniel Hebenstreit, Hebenstreit, Daniel
core   +1 more source

Role of Protein Arginine Methyltransferases and Inflammation in Muscle Pathophysiology

open access: yesFrontiers in Physiology, 2021
Arginine methylation mediated by protein arginine methyltransferases (PRMTs) is a post-translational modification of both histone and non-histone substrates related to diverse biological processes.
Hyun-Kyung So   +4 more
doaj   +1 more source

Plant single-cell and single-cell-type metabolomics

open access: yesTrends in Plant Science, 2014
In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding ...
Biswapriya B, Misra   +2 more
openaire   +3 more sources

Histone H2A monoubiquitination marks are targeted to specific sites by cohesin subunits in Arabidopsis

open access: yesNature Communications, 2023
Histone H2A monoubiquitination (H2Aub1) functions as a conserved posttranslational modification in eukaryotes to maintain gene expression and guarantee cellular identity.
Yu Zhang   +10 more
doaj   +1 more source

Quantitative investigation of calcimimetic R568 on beta cell adhesion and mechanics using AFM single-cell force spectroscopy [PDF]

open access: yes, 2014
In this study we use a novel approach to quantitatively investigate mechanical and interfacial properties of clonal β-cells using AFM-Single Cell Force Spectroscopy (SCFS). MIN6 cells were incubated for 48hrs with 0.5mM Ca2+ ± the calcimimetic R568 (1μM).
Hills, Claire E.   +4 more
core   +1 more source

An atlas of dynamic peripheral blood mononuclear cell landscapes in human perioperative anaesthesia/surgery

open access: yesClinical and Translational Medicine, 2022
Background The number of patients receiving anaesthesia is increasing, but the impact of general anaesthesia on the patient's immune system remains unclear.
Yang‐Yang Wang   +10 more
doaj   +1 more source

A multilayered cross-species analysis of GRAS transcription factors uncovered their functional networks in plant adaptation to the environment

open access: yesJournal of Advanced Research, 2021
Introduction: Environmental stress is both a major force of natural selection and a prime factor affecting crop qualities and yields. The impact of the GRAS [gibberellic acid-insensitive (GAI), repressor of GA1–3 mutant (RGA), and scarecrow (SCR)] family
Moyang Liu   +6 more
doaj   +1 more source

Rehabilitation and the single cell [PDF]

open access: yesCurrent Opinion in Cell Biology, 2007
Cellular damage triggers rapid resealing of the plasma membrane and repair of the cortical cytoskeleton. Plasma membrane resealing results from calcium-dependent fusion of membranous organelles and the plasma membrane at the site of the damage.
William M, Bement   +4 more
openaire   +2 more sources

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