Results 31 to 40 of about 3,900,612 (318)

Exploring cell heterogeneity: applications of single-probe single cell mass spectrometry for subpopulation analysis [PDF]

, 2023
Mass spectrometry (MS) has become an indispensable tool for transformed metabolomics studies, whereas exploring single-cell metabolomic profiles remains a challenge due to limited techniques and suitable algorithms.
Nguyen, Tra
core  

Variations in Cell Surfaces of Estrogen Treated Breast Cancer Cells Detected by A Combined Instrument for Far-Field and Near-Field Microscopy

Analytical Cellular Pathology, 2002
The response of single breast cancer cells (cell line T‐47D) to 17β‐estradiol (E2) under different concentrations was studied by using an instrument that allows to combine far‐field light microscopy with high resolution scanning near‐field (AFM/SNOM ...
P. Perner, A. Rapp, C. Dressler, L. Wollweber, J. Beuthan, K. O. Greulich, M. Hausmann   +6 more
doaj   +1 more source

Dual-well microfluidic technique for single cell isolation and long-term clonal culture

, 2023
[[abstract]]The clonal culture of single cells is widely used for studying cell dynamics and heterogeneity in vitro and producing monoclonal cell populations.
Yeh, CF;Chang, HC;Hsu, CH
core   +1 more source

Protocol to generate fast-dissociating recombinant antibody fragments for multiplexed super-resolution microscopy

STAR Protocols, 2023
Summary: Multiplexed high-density label super-resolution microscopy image reconstruction by integrating exchangeable single-molecule localization (IRIS) enables elucidating fine structures and molecular distribution in cells and tissues.
Qianli Zhang, Akitoshi Miyamoto, Naoki Watanabe   +2 more
doaj   +1 more source

Single cell metabolomics [PDF]

Current Opinion in Biotechnology, 2011
Recent discoveries suggest that cells of a clonal population often display multiple metabolic phenotypes at the same time. Motivated by the success of mass spectrometry (MS) in the investigation of population-level metabolomics, the analytical community has initiated efforts towards MS-based single cell metabolomics to investigate metabolic phenomena ...
Heinemann M, Zenobi R
openaire   +3 more sources

Longitudinal Multi-omics and Microbiome Meta-analysis Identify an Asymptomatic Gingival State That Links Gingivitis, Periodontitis, and Aging

mBio, 2021
A significant portion of world population still fails to brush teeth daily. As a result, the majority of the global adult population is afflicted with chronic gingivitis, and if it is left untreated, some of them will eventually suffer from periodontitis.
Shi Huang, Tao He, Feng Yue, Xiujun Xu, Lijiang Wang, Pengfei Zhu, Fei Teng, Zheng Sun, Xiaohui Liu, Gongchao Jing, Xiaoquan Su, Lijian Jin, Jiquan Liu, Jian Xu   +13 more
doaj   +1 more source

Single-cell assays [PDF]

Biomicrofluidics, 2011
This review presents an overview of literature that describes the applications of microfluidics to assay individual cells. We quantify the content of an individual mammalian cell, so that we can understand what criteria a single-cell assay must satisfy to be successful.
Ryan, Declan, Ren, Kangning, Wu, Hongkai
openaire   +3 more sources

On the mechanical interplay between intra- and inter-synchronization during collective cell migration : a numerical investigation [PDF]

, 2013
Collective cell migration is a fundamental process that takes place during several biological phenomena such as embryogenesis, immunity response, and tumorogenesis, but the mechanisms that regulate it are still unclear.
ALLENA, Rachele, Sharpe, J., AUBRY, Denis, SHARPE, James   +3 more
core   +1 more source

Single-cell genome-wide association reveals a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus [PDF]

, 2022
During pandemics, individuals exhibit differences in risk and clinical outcomes. Here, we developed single-cell high-throughput human in vitro susceptibility testing (scHi-HOST), a method for rapidly identifying genetic variants that confer resistance ...
Ko, Dennis C., Bergstrom, Emma, Brennan, Richard G, Brennan, Richard G., Jack Anderson, Christopher W. Woods, Erica J. Washington, Chiu, Christopher, Harding, Alfred T., Micah T. McClain, McClain, Micah T., Alfred T. Harding, Schott, Benjamin H, Ko, Dennis C, Gregory, Simon G., Zhu, Xinyu, Bourgeois, Jeffrey S, Gregory, Simon G, McClain, Micah T, Emily R. Ko, Heaton, Nicholas S., Dennis C. Ko, Richard G. Brennan, Zoe Gardener, Paterson, Suzanna, Nicholas S. Heaton, Wang, Liuyang, Washington, Erica J., Woods, Christopher W., Liuyang Wang, Heaton, Nicholas S, Benjamin H. Schott, Schott, Benjamin H., Woods, Christopher W, Thomas W. Burke, Anderson, Jack, Christopher Chiu, Bourgeois, Jeffrey S., Suzanna Paterson, Ko, Emily R, Washington, Erika J, Emma Bergstrom, Xinyu Zhu, Harding, Alfred T, Burke, Thomas W., Jeffrey S. Bourgeois, Gardener, Zoe, Ko, Emily R., Burke, Thomas W, Simon G. Gregory   +49 more
core   +1 more source

Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity

Journal for ImmunoTherapy of Cancer, 2023
Background Antineoplastic chemotherapies are dramatically efficient when they provoke immunogenic cell death (ICD), thus inducing an antitumor immune response and even tumor elimination.
Hui Wang, Mayu Sun, Xiaoguang Li, Jingquan Li, Jingyang Li, Huiyi Chen, Xiaoyu Han, Weida Li, Guanghuan Yang, Bao Guo   +9 more
doaj   +1 more source