Results 31 to 40 of about 13,531,309 (317)

Single-Cell Physiology [PDF]

Annual Review of Biophysics, 2015
Single-cell techniques have a long history of unveiling fundamental paradigms in biology. Recent improvements in the throughput, resolution, and availability of microfluidics, computational power, and genetically encoded fluorescence have led to a modern renaissance in microbial physiology.
Taheri-Araghi, Sattar, Brown, Steven D, Sauls, John T, McIntosh, Dustin B, Jun, Suckjoon   +4 more
openaire   +4 more sources

The inhibition of chloride intracellular channel 1 enhances Ca2+ and reactive oxygen species signaling in A549 human lung cancer cells

Experimental and Molecular Medicine, 2019
Cancer: chloride transport protein protects tumors A chloride channel, a membrane protein involved in chloride transport, indirectly regulates calcium signaling to protect cancer cells from free radicals and DNA damage.
Jae-Rin Lee, Jong-Yoon Lee, Hyun-Ji Kim, Myong-Joon Hahn, Jong-Sun Kang, Hana Cho   +5 more
doaj   +1 more source

Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin

Nature Communications, 2023
Force transmission at integrin-based adhesions is important for cell migration and mechanosensing. Talin is an essential focal adhesion (FA) protein that links F-actin to integrins.
Sawako Yamashiro, David M. Rutkowski, Kelli Ann Lynch, Ying Liu, Dimitrios Vavylonis, Naoki Watanabe   +5 more
doaj   +1 more source

A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks

eLife, 2022
Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends.
Danielle Holz, Aaron R Hall, Eiji Usukura, Sawako Yamashiro, Naoki Watanabe, Dimitrios Vavylonis   +5 more
doaj   +1 more source

Single-cell clustering methods.

, 2023
Although advances in single-cell technologies have enabled the characterization of multiple omics profiles in individual cells, extracting functional and mechanistic insights from such information remains a major challenge.
Xudong Han (6702437), Chenghao Situ (15310351), Hui Zhu (87035), Yaling Qi (15310348), Yan Li (23143), Bing Wang (126120), Xuejiang Guo (196111)   +6 more
core   +1 more source

The role of urinary pteridines as disease biomarkers

Pteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Genome-wide identification of nitrate transporter genes from Spirodela polyrhiza and characterization of SpNRT1.1 function in plant development

Frontiers in Plant Science, 2022
Nitrate transporter (NRT) genes that participate in nitrate transport and distribution are indispensable for plant growth, development, and stress tolerance.
Mengli Lv, Tiantian Dong, Jin Wang, Kaijing Zuo   +3 more
doaj   +1 more source

Single-cell states in the estrogen response of breast cancer cell lines [PDF]

, 2014
Estrogen responsive breast cancer cell lines have been extensively studied to characterize transcriptional patterns in hormone-responsive tumors. Nevertheless, due to current technological limitations, genome-wide studies have typically been limited to ...
Andrea Gamba, Nassa, Giovanni, Roberto Amendola, Mario Nicodemi (81682), Sach Mukherjee (19432), Chris J Oates, Francesco Paolo Casale (526999), Nicodemi, M, Weisz, Alessandro, Gamba, A, Jonathan, W., Alessandro Weisz (90872), Alessandro Weisz, Giorgio Giurato (527000), Giorgio Giurato, Gamba, Andrea, Chris J. Oates, Gamba, Andrea Antonio, Armond, Jonathan W., Weisz, A, Amendola, Roberto, Mukherjee, Sach, Casale, Francesco Paolo, Oates, Chris J., Jonathan W. Armond, Mario Nicodemi, Oates, CJ, Giovanni Nassa, Davide Corá, Nassa, G, Corá, Davide, Ro Weisz, Mukherjee, S, Giovanni Nassa (527001), Chris J. Oates (527003), Francesco Paolo Casale, Giurato, Giorgio, Andrea Gamba (181217), Nicodemi, Mario, Sach Mukherjee, Davide Cor?, Giurato, G, Corá, D, Chris, J., Jonathan W Armond, Davide Corá (5649682), Armond, JW, Jonathan W. Armond (527002), Casale, FP, Gamba Andrea, Casale Francesco Paolo, Weisz A, Nicodemi Mario, Giurato G, Giurato Giorgio, Mukherjee Sach, Mukherjee S, Nassa Giovanni, Nassa G, Oates Chris J., Casale FP, Armond Jonathan W., Gamba A, Nicodemi M., Corá D, Corá Davide, CORA', Davide, Armond JW, Oates CJ, Weisz Alessandro   +69 more
core   +1 more source

Luecken Cite-seq human bone marrow 2021 s4d8

, 2023
Dataset published by Luecken et al. 2021 which contains data from human bone marrow measured through joint profiling of single-nucleus RNA and Antibody-Derived Tags (ADTs) using the 10X 3' Single-Cell Gene Expression kit with Feature Barcoding in ...
Single-cell best practices (14656733)
core   +1 more source

Single-cell assays [PDF]

Biomicrofluidics, 2011
This review presents an overview of literature that describes the applications of microfluidics to assay individual cells. We quantify the content of an individual mammalian cell, so that we can understand what criteria a single-cell assay must satisfy to be successful.
Ryan, Declan, Ren, Kangning, Wu, Hongkai
openaire   +3 more sources