Results 131 to 140 of about 13,102,541 (237)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Single top quark production cross section in ATLAS

, 2017
Slides about single top production cross section measurement at ATLAS, to be shown at ...
Dell'Asta, Lidia
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Measurement of the 1-jettiness event shape observable in deep-inelastic electron-proton scattering at HERA

European Physical Journal C: Particles and Fields
The H1 Collaboration reports the first measurement of the 1-jettiness event shape observable $$\tau _1^b$$ τ 1 b in neutral-current deep-inelastic electron-proton scattering (DIS).
H1 Collaboration, V. Andreev, M. Arratia, A. Baghdasaryan, A. Baty, K. Begzsuren, A. Bolz, V. Boudry, G. Brandt, D. Britzger, A. Buniatyan, L. Bystritskaya, A. J. Campbell, K. B. Cantun Avila, K. Cerny, V. Chekelian, Z. Chen, J. G. Contreras, J. Cvach, J. B. Dainton, K. Daum, A. Deshpande, C. Diaconu, A. Drees, G. Eckerlin, S. Egli, E. Elsen, L. Favart, A. Fedotov, J. Feltesse, M. Fleischer, A. Fomenko, C. Gal, J. Gayler, L. Goerlich, N. Gogitidze, M. Gouzevitch, C. Grab, T. Greenshaw, G. Grindhammer, D. Haidt, R. C. W. Henderson, J. Hessler, J. Hladký, D. Hoffmann, R. Horisberger, T. Hreus, F. Huber, P. M. Jacobs, M. Jacquet, T. Janssen, A. W. Jung, J. Katzy, C. Kiesling, M. Klein, C. Kleinwort, H. T. Klest, S. Kluth, R. Kogler, P. Kostka, J. Kretzschmar, D. Krücker, K. Krüger, M. P. J. Landon, W. Lange, P. Laycock, S. H. Lee, S. Levonian, W. Li, J. Lin, K. Lipka, B. List, J. List, B. Lobodzinski, O. R. Long, E. Malinovski, H.-U. Martyn, S. J. Maxfield, A. Mehta, A. B. Meyer, J. Meyer, S. Mikocki, V. M. Mikuni, M. M. Mondal, K. Müller, B. Nachman, Th. Naumann, P. R. Newman, C. Niebuhr, G. Nowak, J. E. Olsson, D. Ozerov, S. Park, C. Pascaud, G. D. Patel, E. Perez, A. Petrukhin, I. Picuric, D. Pitzl, R. Polifka, S. Preins, V. Radescu, N. Raicevic, T. Ravdandorj, D. Reichelt, P. Reimer, E. Rizvi, P. Robmann, R. Roosen, A. Rostovtsev, M. Rotaru, D. P. C. Sankey, M. Sauter, E. Sauvan, S. Schmitt, B. A. Schmookler, G. Schnell, L. Schoeffel, A. Schöning, S. Schumann, F. Sefkow, S. Shushkevich, Y. Soloviev, P. Sopicki, D. South, A. Specka, M. Steder, B. Stella, L. Stöcker, U. Straumann, C. Sun, T. Sykora, P. D. Thompson, F. Torales Acosta, D. Traynor, B. Tseepeldorj, Z. Tu, G. Tustin, A. Valkárová, C. Vallée, P. van Mechelen, D. Wegener, E. Wünsch, J. Žáček, J. Zhang, Z. Zhang, R. Žlebčík, H. Zohrabyan, F. Zomer   +148 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source