Results 21 to 30 of about 4,860 (243)
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Nontensorial transformation optics [PDF]
[EN] We present an alternative version of transformation optics that allows us to mold the flow of light without rotating or scaling the electromagnetic fields.
Barceló, Carlos, García Meca, Carlos
core +2 more sources
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Topological-darkness-assisted phase regulation for atomically thin meta-optics
Two-dimensional (2D) noble-metal dichalcogenides have emerged as a new platform for the realization of versatile flat optics with a considerable degree of miniaturization.
Fei Qin (1315671) +15 more
core +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Topological events on wave dislocation lines: birth and death of small loops, and reconnection
In three-dimensional space, a wave dislocation, that is, a quantized (optical) vortex or phase singularity, is a line zero of a complex scalar wavefunction.
Dennis, MR +5 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Random fractional Fourier transform : stochastic perturbations along the axis of propagation
The fractional Fourier transform (FRT) is known to be optically implementable with use of a medium with a perfect radial quadratic-index profile. Using the quantum-mechanical operator formalism, we examine the effects on the FRT action of such a medium
Abe, Sumiyoshi, Sheridan, John T.
core +1 more source

